DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3168 and CG15221

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001096957.1	Gene:	CG15221 / 32127	FlyBaseID:	FBgn0030331	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	526	Identity:	147/526 - (27%)
Similarity:	250/526 - (47%)	Gaps:	39/526 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 GRKKSVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLD 183
            ||:::  |.|...|  ..||.||.|.|.|:|||.||.||||......::::.:|.|:...:|||.
  Fly    20 GREEN--LSEKPRP--HTFEEAITLTGVGRFHYKLLLICGLCFMGVMVEIMGVSLIMNQMKCDLQ 80

  Fly   184 LNTETKGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRF 248
            .....:|.|.|..|:|:::.::..|.:||::||...|.....:::.|.:.|:||......::|||
  Fly    81 PTLNQQGILASAGFLGVVLSSHAMGFLADTWGRATTLRYALCISSVCSIVSAFSVNIWMLIVFRF 145

  Fly   249 LNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTY 313
            |.|..:.|....::|...||.....|...::.::.|.....:|..::|..|:|..|........:
  Fly   146 LTGFFISGGQACVFSLCGEFHGTGSRIRHVTLLSGFLCMAMIFAPAMAIGILPLRIETIVLGMHF 210

  Fly   314 NSWRIFLLV-CSLPSF-LVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYD 376
            :|||:.||. .|:|.. |||  :..|||:||:||.:|:.|.:|.:.|.||..|:.|.|.||
  Fly   211 SSWRVLLLANVSIPLLALVG--ISALPETPKYLLVQGRGDESLEVLRSIFANNSGRDPSEY---- 269

  Fly   377 LEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSPILRF-------TIVSITINFTFHIGYYGL 434
             .|.|..|||.|...:.    :.|.:|..|.::...:..|       |:....|.|..:....|:
  Fly   270 -PVKEVALESGGVSLSD----VHGFLDAVRLVWHQTVPLFYRARLWHTLNICCIQFIIYFLAQGI 329

  Fly   435 LMWFPELFNRFEEYEKAFPDQSAGVCAVTD-YVVNLAKEQSNNGTCSSDIPQSVFMESLISLASA 498
            .||||.:.:......    .::..:|.|.. :.:|.:.|...: :||.::..|.:...:|..|..
  Fly   330 FMWFPTILDELGTRN----GENTLLCTVLQGFNINSSSEDEAS-SCSVEVDTSTYQVMIIIAACF 389

  Fly   499 LPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVSAI-FSGAISAANAALDCL 562
            :...|:....:|.:|:|..|:|..:...||...:::|....  |||.|: ...||......:..:
  Fly   390 VVIYLIFAYIIDYMGKKNLLMAWMVLTMICLVALHYVEQFA--LVVIALTVVMAIGNCGGLVSTI 452

  Fly   563 ITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLDNYCPSPTFIVSGLLIGGGLMCLL---LP 624
            ..|.:||.:.|.|:...|:..|||.::|:.::.:||...|....:.:..|::   |:|.|   ||
  Fly   453 AMEFYPTHINAMGMCFIMMVGRLGAVVGSNILGRLLFASCDPIFWALLALVV---LLCTLGYFLP 514

  Fly   625 NTTRKE 630
            ...|.:
  Fly   515 EKARSQ 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	125/459 (27%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	128/482 (27%)
CG15221	NP_001096957.1	2A0115	36..488	CDD:273327	130/469 (28%)
CG15221	NP_001096957.1	MFS	51..488	CDD:119392	121/454 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.070