DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3168 and Slc22a20

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001381833.1	Gene:	Slc22a20 / 293686	RGDID:	1311460	Length:	556	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	120/467 - (25%)
Similarity:	208/467 - (44%)	Gaps:	94/467 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 ILPSA---ECDLDLNTET-KGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVAS 234
            |.||.   |.||.....| :....||...|::|||..:||:||..|||..|:......|.....:
  Rat   117 IFPSTIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGSLADRLGRKAPLVWSYLQLAVSGAVT 181

  Fly   235 SFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKR---GSMLSFMAAFWTFGNLFVASLA 296
            ::..::|.:.:||||.|....|......|...|:.|...|   |.:|.|.   :|.|.|.:|.:|
  Rat   182 AYVGSFSAYCIFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAGILLGFS---FTLGQLILAGVA 243

  Fly   297 WLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLL-FYLPESPKFLLTRGKKDRALAIFRGI 360
            :||.|              ||......|.| |||.||. ::||||.::||..||..:|:...|.:
  Rat   244 YLIRP--------------WRWLQFAVSAP-FLVFFLYSWWLPESSRWLLLHGKAQQAVQNLRKV 293

  Fly   361 FVTNTKRRPDEYMVYDLEVDEKLLESNGNVKNKYS--RMISGMVDHSRALFKSP-ILRFTIVSIT 422
            .:.|.::...|.:..::        .:..::|:::  |..:.::|    ||::| |.:.|...:.
  Rat   294 AMMNGRKAEGERLTIEV--------VSSYIQNEFASVRTSNSILD----LFRTPGIRKVTCCLMM 346

  Fly   423 INFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSV 487
            :.|:..:.||||.|          :.:|         ..::.|:|                 |::
  Rat   347 VWFSNSVAYYGLAM----------DLQK---------FGLSIYLV-----------------QAL 375

  Fly   488 FMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNL--VVSAIFSG 550
            |  .:|.    :||.|:|...|..:||:..:.:..:.||:......||...:|.|  |.:|:..|
  Rat   376 F--GIID----IPAMLVATTTMIYVGRRATVSSFLVLAGLMVIANMFVPEDLQTLRTVQAALGKG 434

  Fly   551 AISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIV-----IAQLLDNYCPSPTFIVS 610
            .::::...:.....|::||::|..|:..:.|.|||||:...::     |:.:|    |..:|..:
  Rat   435 CLASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLAAPLITTLGEISPVL----PPVSFGAT 495

  Fly   611 GLLIGGGLMCLL 622
            .:|.|..::|.|
  Rat   496 SVLAGMAVICFL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	113/441 (26%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	120/467 (26%)
Slc22a20	NP_001381833.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	120/467 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910