DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3168 and SPBC8E4.01c

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_596846.2	Gene:	SPBC8E4.01c / 2541258	PomBaseID:	SPBC8E4.01c	Length:	572	Species:	Schizosaccharomyces pombe

Alignment Length:	579	Identity:	123/579 - (21%)
Similarity:	225/579 - (38%)	Gaps:	110/579 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 GGKGGKGRKKSVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPS 177
            |.|..:....:|||.:    :....:......|..|..:.|:.:.|:....:..|:..::.:.|.
pombe    11 GSKSDEYNDDAVPLDQ----VEEGAQERRYYLGLTKREFKLMMLAGVGFFLDSYDLFIINLVTPI 71

  Fly   178 AEC----DLDLNTETK--------GWLNSIIFIGMMVGAYFWGSIADSFGRK------KVLIVIS 224
            .|.    .::.....|        |.:|:...||.:.|...:|.:.|.||||      .|:::|:
pombe    72 FEYLYWGGIEKGPTGKGHYPSGIRGLVNASANIGNIFGQLLFGFMGDFFGRKFVYGKEMVIVIIA 136

  Fly   225 FMNAFCIVASSFSQTYSFFMLF--RFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTF 287
            .:....:..|..|.......:|  |:|.|..:||..|:..:..:|.....:||:::|.:.||..|
pombe   137 TVLVIAMPKSIHSPLSKMMWVFCWRWLLGVGIGGDYPMSAAITSERSKIKRRGTLISLIFAFQGF 201

  Fly   288 GNLFVASLAWLIIPRTIG-FTTP------YFTYNS-WRIFLLVCSLPSFLVGFLLFYLPESPKFL 344
            |.| ..::..:|:   :| |..|      |..... ||:...:..:|:  :|.|:      |:.:
pombe   202 GTL-AGAIVTIIL---LGCFEHPLNREGHYHKLEGVWRLQFGLALVPA--IGVLI------PRLI 254

  Fly   345 LTRGK---KDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGN-----VKNKYSRMISGM 401
            :...|   ..:||....|       :.|..:...|.|.:.|...|:|:     ..::|    :..
pombe   255 MKESKSYENSKALNSAEG-------KDPKAFFNTDDEDNMKKSSSHGDSEVVEASDRY----ANQ 308

  Fly   402 VDHSRALFKSPILRFTIVSITINFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVC----AV 462
            .|.:.|...:...:|..|:...|.:..|.|:.....|..|.             ...||    .:
pombe   309 ADAADAEVDNIEKQFAAVTTPENSSGFITYFRQWRHFKHLL-------------GTSVCWFLLDI 360

  Fly   463 TDYVVNLAKEQS----NNGTCSSDIPQSVFMES-----LISLASALPANLLAILGMDMLGRKFFL 518
            ..|.|||  .||    |.|..:........|::     :|::|..:|.....:..:::||||:..
pombe   361 AFYGVNL--NQSVILKNIGFSTGTNEYRTLMKNAIGNLIIAVAGYVPGYWFNVFLVEILGRKWIQ 423

  Fly   519 IAGTMTAGICSALMYFVRSSVQN------LVVSAIFSGAISAANAALDCLITEVFPTKLRATGVA 577
            :.|.:..|:..|::....:.:..      .|::.:||.  ...|:.......||||.::|.|...
pombe   424 LQGFVITGLMFAILAGRWNEISTGGRFACFVIAQLFSN--FGPNSTTFIYPAEVFPARVRGTAHG 486

  Fly   578 ISMVAARLGGIIGNIVIAQLLDNYCP------SPTFIVSGLLIGGGLMCLLLPNTTRKE 630
            :|....:.|.|     :|.||.|:..      :..:|..|.:.||.|..||||.|..::
pombe   487 VSAALGKCGAI-----LASLLFNFLTGVIGYGNVMWIFCGCMWGGILFTLLLPETKGRD 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	103/503 (20%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	111/529 (21%)
SPBC8E4.01c	NP_596846.2	2A0109	27..547	CDD:129965	118/559 (21%)
SPBC8E4.01c	NP_596846.2	MFS	48..534	CDD:119392	112/530 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1933
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940