Protein Alignment CG3168 and Slc22a5

DIOPT Version :10

• Sequence 1: NP_572345.1
• Gene: CG3168 / 31612
• FlyBaseID: FBgn0029896
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Alignment Length: 650
• Identity: 142/650 - (21%)
• Similarity: 236/650 - (36%)
• Gaps: 195/650 - (30%)

  Fly    13 FYNVEAGLQPNYNQSAASNQASNHPTGQANAPATGNATSHIDNRAIIQPYSLGTGPKQPE----Y 73
            |:.:.|.:.||.....:....:..|..:...|.|.|.:|...|.:|  |.....|.:.|:    |
Mouse    22 FFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLSSAWRNHSI--PLETKDGRQVPQKCRRY 84

  Fly    74 QFAA----DNRGYEPDSHANGKQQDVERDAPDGGHGGHGPPGKGGKGGKGRKKSVPLPEPTAPIV 134
            :.|.    ...|.||     |:..|:|:
Mouse    85 RLATIANFSELGLEP-----GRDVDLEQ------------------------------------- 107

  Fly   135 ANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWL-NSIIFI 198
              .|:...|.|:                ..:.||...:.:   .|.||....:.|..| .|:.|:
Mouse   108 --LEQESCLDGW----------------EYDKDVFLSTIV---TEWDLVCKDDWKAPLTTSLFFV 151

  Fly   199 GMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSF-FMLFRFLNGAALGGSGPVIW 262
            |:::|::..|.::|.||||.||.:...|.    ...||.|.:|. |.:|..|  ..|.|.|. |.
Mouse   152 GVLMGSFISGQLSDRFGRKNVLFLTMGMQ----TGFSFLQVFSVNFEMFTVL--FVLVGMGQ-IS 209

  Fly   263 SYFAEFQPKAKRGSML---SFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTY--NSWRIFLLV 322
            :|.|.|    ..|:.:   |....|.|.|.....:..::::        |.|.|  ..||:.||.
Mouse   210 NYVAAF----VLGTEILSKSIRIIFATLGVCIFYAFGFMVL--------PLFAYFIRDWRMLLLA 262

  Fly   323 CSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFR------GIFVTNT-----------KRRPD 370
            .::|..|.|.|.:::||||::|:::|:...|..|.|      ||...:|           ..:|.
Mouse   263 LTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSELQDLNSTKPQ 327

  Fly   371 EYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSPILRFTIVSITINFTFHIGYYGLL 435
            .:.:|||            ::.:..|:|                  ||:||.:..|..:||:||.
Mouse   328 LHHIYDL------------IRTRNIRVI------------------TIMSIILWLTISVGYFGLS 362

  Fly   436 MWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFMESLISLASALP 500
            :..|.|..                                          .:::...:..|..:|
Mouse   363 LDTPNLHG------------------------------------------DIYVNCFLLAAVEVP 385

  Fly   501 ANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVSAIFSG--AISAANAALDCLI 563
            |.:||.|.:..|.|::.:.|.....|.....|..|.|.:..|..:.:..|  .|::|.:.:....
Mouse   386 AYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGITSAYSMVYVYT 450

  Fly   564 TEVFPTKLRATGVAISMVAARLGGIIG-NIVIAQLLDNYCPSPTFIVSG-LLIGGGLMCLLLPNT 626
            .|::||.:|..||.:|..|:|||.|:. ..|.....|.:.|   :|:.| |.|...::.|..|.:
Mouse   451 AELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLP---YILMGSLTILTAILTLFFPES 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_572345.1	synapt_SV2	<137..626	CDD:130366	120/516 (23%)
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	142/649 (22%)