Protein Alignment CG3168 and slc22a8

DIOPT Version :10

• Sequence 1: NP_572345.1
• Gene: CG3168 / 31612
• FlyBaseID: FBgn0029896
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: XP_002937554.2
• Gene: slc22a8 / 100490266
• XenbaseID: XB-GENE-22061134
• Length: 556
• Species: Xenopus tropicalis
• Alignment Length: 592
• Identity: 141/592 - (23%)
• Similarity: 241/592 - (40%)
• Gaps: 128/592 - (21%)

  Fly    58 IIQPYSLGTGPKQPEYQFAADNRGYEPDSHANGKQQDVERDAPDGGHGGHGPPGKGGKGGKGRKK 122
            ::|.:|...    |:::..|::.||:.:|            ..:.|:               .:.
 Frog    36 LLQNFSAAI----PDHKCKANDTGYQSNS------------TDETGY---------------ERL 69

  Fly   123 SVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEM-------------DVISMSFI 174
            |.||.....|     :|.:|   |.:..:.::......:.|.|:             |..|.:.|
 Frog    70 SAPLDANGQP-----DRCLE---YVEIQWRMVGSNSTWNNSSELATRPCTIGWEYSKDEFSSTII 126

  Fly   175 LPSAECDLDLNTETKGWLNSIIFI-GMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQ 238
               .|.||....:|:..|...|:: |::|||...|.::|.:||:.:||...|..|...|.::||.
 Frog   127 ---TEWDLVCGRKTRRQLAQSIYMGGVLVGAIILGGLSDRYGRRALLIWSYFQLAVSGVCAAFSP 188

  Fly   239 TYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAF-WTFGNLFVASLAWLIIPR 302
            .|..:.:||||.|.||.|.|....:...|:.|...| ::...:|.| :|.|.|.:|.||
 Frog   189 NYLSYCIFRFLTGMALSGIGLNTTALIVEWVPTRVR-TVTGTLAGFSYTAGQLLLAGLA------ 246

  Fly   303 TIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNTKR 367
                    :....||...|..|||.|:.....::.|||.::|:..||.::|:...|.:...|.|:
 Frog   247 --------YGMRDWRWLQLCVSLPFFIYFLYAWWFPESARWLVLSGKPEKAVKEIRKVANLNGKK 303

  Fly   368 RPDEYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSPILRFTIVSITINFTFHIGYY 432
            ...|.:..: .:..::::...:.|:.||     ::|..|.   :.|.|.:.....:.|:....||
 Frog   304 EEGEKITLE-SLKSEMIKELASAKSSYS-----VIDLVRT---NTIRRISCALSLVWFSTSFAYY 359

  Fly   433 GLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFMESLISLAS 497
            ||.|.. :.||                                         .|:::..:|..|.
 Frog   360 GLAMDL-QKFN-----------------------------------------VSIYLIQVIFGAV 382

  Fly   498 ALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVS-AIF-SGAISAANAALD 560
            ..||.|::...|..:||||......:..||......||.:.:|.:..| |:| .|.::|:.:.:.
 Frog   383 DFPAKLVSATAMIYVGRKFTQFMSLILGGIAIIANIFVPNELQTVRTSLAVFGKGCLAASFSCIF 447

  Fly   561 CLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLDNYCP-SPTFIVSGLLIGGGLMCLLLP 624
            ...||::||.:|.:|:.:....||:|||:..:|  ::|....| .|..|..|..|..||....||
 Frog   448 LYTTELYPTVIRQSGLGMCSTMARIGGIVAPLV--KILGELYPFVPLLIYGGAPIISGLCVFFLP 510

  Fly   625 NTTRKEL 631
            .|..|.|
 Frog   511 ETVNKPL 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_572345.1	synapt_SV2	<137..626	CDD:130366	126/506 (25%)
slc22a8	XP_002937554.2	MFS_SLC22A6_OAT1_like	105..510	CDD:341004	119/475 (25%)