DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3168 and sv2bb

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_005161575.1	Gene:	sv2bb / 100006427	ZFINID:	ZDB-GENE-030131-2789	Length:	687	Species:	Danio rerio

Alignment Length:	688	Identity:	185/688 - (26%)
Similarity:	304/688 - (44%)	Gaps:	129/688 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 YSLGTGPKQPEY-QFAADNRGYEPDSHANGKQQDVERDAPDGGHGGHGPPGKGGKGGKGRKKSVP 125
            |..|.|.....| |...|..||:.|...  :::|...||.:    ||   .:..:..:|..:.:|
Zfish    10 YHQGDGDSYGTYGQGGQDGYGYQTDYPP--QEEDAASDATE----GH---DEDDQMYEGEYQGIP 65

  Fly   126 LPE---------------PT------APIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVI 169
            .|:               ||      ..:...:|..:|.||:|||.:.|..:.||...::.::..
Zfish    66 HPDEVKAARRAARAKARTPTDTVSELEELAEQYEDIMEDCGHGKFQWTLFVVLGLALMADSVECF 130

  Fly   170 SMSFILPSAECDLDLNTETKGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVAS 234
            .::.:|||||.|:.|:...||.|..|:|:|||.||:.||.:||..||:|.||::..||......|
Zfish   131 VVALVLPSAEKDMCLSHAEKGMLGLIVFLGMMFGAFIWGGLADKVGRRKCLIIVLAMNCISAFFS 195

  Fly   235 SFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLI 299
            ||:|.|.||:.||..:|..:|||.|:::|||:||....|||..||::..||..|.::.:..||.|
Zfish   196 SFAQGYGFFLFFRLFSGIGIGGSVPIVYSYFSEFLQMDKRGEHLSWLCMFWMMGGIYASFTAWGI 260

  Fly   300 IPR-TIGFTT-PYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFV 362
            ||| ..||:. ..|.::|||:|:|||:||:......|.::||||:|||...|.|.|..|.:.:..
Zfish   261 IPRYGWGFSMGTEFQFHSWRVFVLVCALPAIAAFVGLMFMPESPRFLLENAKHDEAWMILKQVHD 325

  Fly   363 TN--TKRRPDE-YMVYDLEV----DEKLLESNGNVKNKYSRMISGMVDHSRALFKSPILRF---- 416
            ||  .|.:|:: :.|..:..    :::.:|........:.|.:...:..::.:.|:.:..|
Zfish   326 TNWRAKGQPEKVFTVTQIRTPKTQEDEFIEIQTATGTAFQRWVVRTLTLTKLVIKNVLSLFGREL 390

  Fly   417 ---TIVSITINFTFHIGYYGLLMWFPELFN--RFEEYEK-------------------------- 450
               |::...|.||....||||.:|||::..  :.||||.
Zfish   391 RLATLLMAIIWFTMAFSYYGLSVWFPDMIKHLQHEEYESKVKVFHREKVEQFHFNFSLENQVHKE 455

  Fly   451 ----------------AFPD------------------QSAGVCAVTDYVVNLAKEQ-------- 473
                            .|.|                  ::..:.:...|..:|.:|:
Zfish   456 GEYINDKFINIEMKSVKFEDSLFVDCFFENVRSTETMFENCTIRSTVFYDTDLYEEKFIDCTMEN 520

  Fly   474 ----SNNGTCSSDIPQS----VFMESLISLASALPANLLAILGMDMLGRKFFLIAGTM--TAGIC 528
                .|...|..|..:.    :::.|.:...:.||.|:::.|.||.:|| ..:|.|:|  :|| |
Zfish   521 VTFLHNKKGCHLDYEEDNDVLIYLVSFLGSLAVLPGNIISALFMDKIGR-IKIIGGSMLVSAG-C 583

  Fly   529 SALMYFVRSSVQNLVVSAIFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIV 593
            :..::...|....:....:|.|...||...:..:..|::|...|||.........:|..|:|:.:
Zfish   584 TFFLFLSFSQAAIIAWQCLFYGVSVAAWNGIQVITVELYPASKRATAFGFLNAMCKLAAILGSSI 648

  Fly   594 IAQLLDNYCPSPTFIVSGLLIGGGLMCLLLPNTTRKEL 631
            .|..:......|..:....|:.||::.|.||.|..|.|
Zfish   649 FASFIGITKVIPILLSFAALVSGGVLALKLPETREKVL 686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	150/544 (28%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	153/564 (27%)
sv2bb	XP_005161575.1	MFS	115..>308	CDD:119392	81/192 (42%)
		Pentapeptide_4	457..532	CDD:290330	7/74 (9%)
		MFS	538..>676	CDD:119392	33/139 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59613
OrthoDB	1	1.010	-	-		D208328at33208
OrthoFinder	1	1.000	-	-		FOG0001322
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102121
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X658
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830