DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3168 and slc22a7b.3

DIOPT Version :9

Sequence 1:	NP_001284957.1	Gene:	CG3168 / 31612	FlyBaseID:	FBgn0029896	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	XP_001337264.3	Gene:	slc22a7b.3 / 100001772	ZFINID:	ZDB-GENE-131120-103	Length:	546	Species:	Danio rerio

Alignment Length:	551	Identity:	124/551 - (22%)
Similarity:	213/551 - (38%)	Gaps:	161/551 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 SVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAEC------- 180
            |||..|..:|:      :..:..:.:|..       |:::|...|       ||..||
Zfish    72 SVPTQEDGSPV------SCHMFSHPQFQL-------LINSSSSSD-------LPVVECQNGWHFD 116

  Fly   181 ----------DLDLNTETKGWLN----SIIFIGMMVGAYFWGSIADSFGRKKVLIV--ISFMNAF 229
                      ..||..:.:| ||    :|.|:|:|.||.|:|.::|.||||.:|:|  ||.| ||
Zfish   117 NSTFISTLATQWDLVCDNRG-LNKAVATIFFVGVMFGAAFFGGMSDRFGRKPMLLVSYISGM-AF 179

  Fly   230 CIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQ----PKAKRGSMLSFMAAFWTFGNL 290
            .: ||.||.:::.|.:.||.:|..:  :|.||.|.....:    ...:..|::..||  |..|:.
Zfish   180 AL-ASVFSTSFTMFAVLRFFSGFTI--TGIVIVSSVLNLEWVDIEHRRLVSIIDSMA--WAVGST 239

  Fly   291 FVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALA 355
            .:|.:|:.|              ..||...:..:.|..|...|.:::|||.::|:..|..::|..
Zfish   240 SLALIAYFI--------------RDWRWLTVAVTSPLVLCTILWWWVPESARWLIANGDVEKAHY 290

  Fly   356 IFRGIFVTNTKRRPDEYMVYDLEVDEKL------LESNGNVKNKYSRMISGMVDHSRALFKSPIL 414
            ......|.|.|          .||..::      :..:...|.||:.:         .|.::|.:
Zfish   291 YLHKCAVMNRK----------AEVTSRIKPEALAISVSDQGKKKYTYL---------DLVRTPKM 336

  Fly   415 R----------FTIVSITINFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNL 469
            |          |.:.::|...:.:|..:||.|:                        :|.:|..
Zfish   337 RKLAMLTGTVWFCVATMTYGISLNITGFGLNMY------------------------LTQFVYG- 376

  Fly   470 AKEQSNNGTCSSDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYF 534
                                      |..:|:.|:....::.:||:.......:.|||...:..|
Zfish   377 --------------------------AIEVPSKLIVYYLLEKIGRRKTEAGAQLFAGISLMINIF 415

  Fly   535 VRSS--VQNLVVSAIFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQL 597
            :...  :...||:.:..|...||...:....:|::||.||..|:..:...||||..:..:|:  |
Zfish   416 IPKDQWIGRTVVAVLGKGFAVAAFCTIVLYSSELYPTVLRQNGMGYNSFLARLGVSVAPLVL--L 478

  Fly   598 LDNYCP--SPTFIVSGLLIGGGLMCLLLPNT 626
            ||.:..  |.|.:.|..|| ..::...||.|
Zfish   479 LDTFWGQFSQTILCSVALI-ASVVAWNLPET 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3168	NP_001284957.1	2A0115	149..598	CDD:273327	108/493 (22%)
CG3168	NP_001284957.1	MFS	154..623	CDD:119392	115/515 (22%)
slc22a7b.3	XP_001337264.3	2A0119	12..516	CDD:273328	124/551 (23%)
slc22a7b.3	XP_001337264.3	MFS	141..506	CDD:119392	103/457 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910