DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14440 and ZNF639

DIOPT Version :10

Sequence 1:NP_572343.1 Gene:CG14440 / 31610 FlyBaseID:FBgn0029894 Length:318 Species:Drosophila melanogaster
Sequence 2:NP_057415.1 Gene:ZNF639 / 51193 HGNCID:30950 Length:485 Species:Homo sapiens


Alignment Length:199 Identity:32/199 - (16%)
Similarity:69/199 - (34%) Gaps:47/199 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   149 QQQQQQHPLHHHLSAGVVVEASQLGGV-----PGLANLGVPHLSAQQSVTQQGQSSRAQ------ 202
            ::::..||..:..|:|:...|....|:     ..:.::..|.|....:......:..:.      
Human     8 RKRKTLHPSRYSDSSGISRIADGFNGIFSDHCYSVCSMRQPDLKYFDNKDDDSDTETSNDLPKFA 72

  Fly   203 ---KAARRRSNESIEARERRLERNAARMRDKRA------------------KESEAEYRVRLAKN 246
               ||..|..|..:.:...|:..:.|...:|.|                  .:.|:...|..|::
Human    73 DGIKARNRNQNYLVPSPVLRILDHTAFSTEKSADIVICDEECDSPESVNQQTQEESPIEVHTAED 137

  Fly   247 ----AEANRVRRQNETEVQRTLRLMKNAARQRLRRASETVEERKKRLAKAAERMRIARASAPKVI 307
                .|.:.:....:.|.:       |.:.:.|:  .:|.||...:|.|..::.:....:|.:  
Human   138 VPIAVEVHAISEDYDIETE-------NNSSESLQ--DQTDEEPPAKLCKILDKSQALNVTAQQ-- 191

  Fly   308 KPPL 311
            |.||
Human   192 KWPL 195

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14440NP_572343.1 Smc <189..>303 CDD:440809 20/144 (14%)
ZNF639NP_057415.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20 2/11 (18%)
C2H2 Zn finger 235..255 CDD:275368
C2H2 Zn finger 262..283 CDD:275368
C2H2 Zn finger 291..307 CDD:275368
Interaction with CTNNA2. /evidence=ECO:0000269|PubMed:16182284 371..455
C2H2 Zn finger 376..397 CDD:275368
C2H2 Zn finger 405..425 CDD:275368
C2H2 Zn finger 433..454 CDD:275368
C2H2 Zn finger 462..482 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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