Protein Alignment CG14440 and IKZF2

DIOPT Version :10

• Sequence 1: NP_572343.1
• Gene: CG14440 / 31610
• FlyBaseID: FBgn0029894
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: XP_011509104.1
• Gene: IKZF2 / 22807
• HGNCID: 13177
• Length: 533
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 44/230 - (19%)
• Similarity: 77/230 - (33%)
• Gaps: 70/230 - (30%)

  Fly     4 LTVKSLLGGILFATSSIGLLLNLLVVSPVFQLAFAKDKSSIYVISSVNIINDILHLLITTFYLAP 68
            :.:.:.|..::..::.|.:|...::|..:|.|         |.:|           |||..:|..
Human   128 ILIMATLMALIVKSAQIVVLTGFVMVFTLFLL---------YGLS-----------LITLAFLMS 172

  Fly    69 TIILNSFIFSDERNGNLTVFISFIFMVLWYIGNITQI---VMAVNRWAVICILRSSMFT------ 124
            .:|...|         ||..:.|:.:|.|.|.....:   :.|...| .:|:|....||
Human   173 VLIKKPF---------LTGLVVFLLIVFWGILGFPALYTRLPAFLEW-TLCLLSPFAFTVGMAQL 227

  Fly   125 ---------------KRN--LIICFSFTLVFAVAKSYIV-----------QYVFPCCSFLVDQTV 161
                           .:|  |||...|.|||... .|:|           :|...|......::.
Human   228 IHLDYDVNSNAHLDSSQNPYLIIATLFMLVFDTL-LYLVLTLYFDKILPAEYGHRCSPLFFLKSC 291

  Fly   162 LSYSYFQIENIT--NYTDHSDIPLNALSSIVPVIC 194
            ..:.:.:..::.  |.||....|.:....:.|..|
Human   292 FWFQHGRANHVVLENETDSDPTPNDCFEPVSPEFC 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14440	NP_572343.1	Smc	<189..>303	CDD:440809	2/6 (33%)
IKZF2	XP_011509104.1	C2H2 Zn finger	121..141	CDD:275368	1/12 (8%)
		zf-H2C2_2	134..158	CDD:463886	4/23 (17%)
		C2H2 Zn finger	149..169	CDD:275368	8/39 (21%)
		zf-H2C2_2	161..186	CDD:463886	9/44 (20%)
		C2H2 Zn finger	177..197	CDD:275368	7/28 (25%)
		C2H2 Zn finger	205..226	CDD:275368	6/21 (29%)