DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14440 and Ikzf3

DIOPT Version :10

Sequence 1:NP_572343.1 Gene:CG14440 / 31610 FlyBaseID:FBgn0029894 Length:318 Species:Drosophila melanogaster
Sequence 2:NP_035901.1 Gene:Ikzf3 / 22780 MGIID:1342542 Length:507 Species:Mus musculus


Alignment Length:126 Identity:26/126 - (20%)
Similarity:46/126 - (36%) Gaps:30/126 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   191 SVTQQGQSSRAQK---------------AARRRSNESIEARERRLERN-----AARMRDKRAKES 235
            |.||:|...|..|               |.:||...:...|...:|:.     ..|...:|:...
Mouse   153 SFTQKGNLLRHIKLHTGEKPFKCHLCNYACQRRDALTGHLRTHSVEKPYKCEFCGRSYKQRSSLE 217

  Fly   236 EAEYRVRL---------AKNAEANRVRRQNETEVQRTL-RLMKNAARQRLRRASETVEERK 286
            |.:.|.|.         |.:.||..::.:..:|....| ||..|.|:::.....:.:.|::
Mouse   218 EHKERCRAFLQNPDLGDAASVEARHIKAEMGSERALVLDRLASNVAKRKSSMPQKFIGEKR 278

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14440NP_572343.1 Smc <189..>303 CDD:440809 26/126 (21%)
Ikzf3NP_035901.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..85
COG5048 <105..>218 CDD:227381 13/64 (20%)
C2H2 Zn finger 119..139 CDD:275368
zf-H2C2_2 132..156 CDD:463886 1/2 (50%)
C2H2 Zn finger 147..167 CDD:275368 6/13 (46%)
C2H2 Zn finger 175..195 CDD:275368 4/19 (21%)
C2H2 Zn finger 203..219 CDD:275368 2/15 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 370..396
Mediates homodimerization and heterodimerization. /evidence=ECO:0000250|UniProtKB:Q9UKT9 450..502
Blue background indicates that the domain is not in the aligned region.

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