DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14442 and ZNF613

DIOPT Version :9

Sequence 1:NP_572342.1 Gene:CG14442 / 31609 FlyBaseID:FBgn0029893 Length:1034 Species:Drosophila melanogaster
Sequence 2:NP_001026891.2 Gene:ZNF613 / 79898 HGNCID:25827 Length:617 Species:Homo sapiens


Alignment Length:278 Identity:46/278 - (16%)
Similarity:95/278 - (34%) Gaps:49/278 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    67 HQQQQQQHQQQQQQFQQQHLH-------QQQQDQLQFQQQH--LQLYAPLKQQQL---QQQQSQQ 119
            |.|...|.|:..::.:|.|.|       .|::.....:|.|  ..|:..:.:..|   .|.:..:
Human    86 HLQMHSQKQRCLKRVEQCHKHNAFGNIIHQRKSDFPLRQNHDTFDLHGKILKSNLSLVNQNKRYE 150

  Fly   120 PPTPLGPTSSASSASITGASTTGHQQRWNES--PEARQRRLARNAERMRERRQRESEE-----EY 177
            ....:|......|     .....|:|..||.  ||. ...:..|::.::.:|.:..::     |.
Human   151 IKNSVGVNGDGKS-----FLHAKHEQFHNEMNFPEG-GNSVNTNSQFIKHQRTQNIDKPHVCTEC 209

  Fly   178 RKRLLRNAEANRQRRQNESDIERAMRLVRNAARQRLRRAMESPDQRAKRLAKLAERMRMYR-ASE 241
            .|..|:.:.....:|.:..:......:...|..::........:...::..:..|..:.:| .|:
Human   210 GKAFLKKSRLIYHQRVHTGEKPHGCSICGKAFSRKSGLTEHQRNHTGEKPYECTECDKAFRWKSQ 274

  Fly   242 TNDQRKLRLAEMAARARQRIANESPEERKERLRKLNDYAKKVREKKKVLKHVVVHGGSS----SV 302
            .|..:|:...|.:...                   :|..|...:|.:::.|..||.|..    |:
Human   275 LNAHQKIHTGEKSYIC-------------------SDCGKGFIKKSRLINHQRVHTGEKPHGCSL 320

  Fly   303 VVSTPTSSSSSTDQQHHH 320
            .....:..|..|:.|..|
Human   321 CGKAFSKRSRLTEHQRTH 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14442NP_572342.1 PRK11675 <692..>709 CDD:183272
ZNF613NP_001026891.2 KRAB 8..67 CDD:214630
KRAB 8..47 CDD:279668
COG5048 176..531 CDD:227381 27/183 (15%)
C2H2 Zn finger 206..226 CDD:275368 4/19 (21%)
C2H2 Zn finger 234..254 CDD:275368 1/19 (5%)
zf-H2C2_2 247..269 CDD:290200 1/21 (5%)
C2H2 Zn finger 262..282 CDD:275368 5/19 (26%)
C2H2 Zn finger 290..310 CDD:275368 4/38 (11%)
C2H2 Zn finger 318..338 CDD:275368 4/19 (21%)
zf-H2C2_2 331..353 CDD:290200 3/8 (38%)
C2H2 Zn finger 346..366 CDD:275368
C2H2 Zn finger 374..394 CDD:275368
zf-H2C2_2 386..411 CDD:290200
C2H2 Zn finger 402..422 CDD:275368
zf-H2C2_2 414..439 CDD:290200
C2H2 Zn finger 430..450 CDD:275368
C2H2 Zn finger 458..478 CDD:275368
zf-H2C2_2 471..493 CDD:290200
zf-C2H2 484..506 CDD:278523
C2H2 Zn finger 486..506 CDD:275368
zf-H2C2_2 499..523 CDD:290200
C2H2 Zn finger 514..530 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165148420
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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