DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14442 and Zfp639

DIOPT Version :9

Sequence 1:	NP_572342.1	Gene:	CG14442 / 31609	FlyBaseID:	FBgn0029893	Length:	1034	Species:	Drosophila melanogaster
Sequence 2:	NP_001074376.1	Gene:	Zfp639 / 683504	RGDID:	1585689	Length:	485	Species:	Rattus norvegicus

Alignment Length:	331	Identity:	63/331 - (19%)
Similarity:	103/331 - (31%)	Gaps:	96/331 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   683 PQIVTTPVGRGRPRKNPLPSEEQLKVNSLLEQELNQMLSAPQLATSTPRRGRPLSQASQQHHQEL 747
            |:.......|.|.:...:||    .|..:||..:........:.......|.|  ::..||..|.
  Rat    69 PKFTDGTKARSRSQSCLVPS----PVLRILEHTVFSTEKPADVEICDEECGSP--ESGHQHTHEE 127

  Fly   748 SQIHVHSTADGDSRTPVLTPRRSGANKY--------------ETEEEKRIRLDKMAAHQRAVRAN 798
            |.|.||::.|    .|:.....:.:..|              :|:||...:|.|:....:|  :|
  Rat   128 SPIEVHTSED----VPIAVEVHAISEDYDIEAENNSSESLLDQTDEEPPAKLCKILDKSQA--SN 186

  Fly   799 ETPEQRATRLQKLSER--------------ARLKRAQIRATENTDERKERLSKQAEYARMRRMRS 849
            .|.:|:...|:..|..              :.||:..|...:.||....|:.|::....|..:.
  Rat   187 VTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHVILKHKRTDSNVCRVCKESFSTNMLLIE- 250

  Fly   850 HTPRSSSATSTEFRAKTEEEDE--CQ---------------DDDTSAEHHMYESEAVSVTGTGSD 897
                         .||..|||.  |:               ..||....|:|..|...|..:.|.
  Rat   251 -------------HAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSS 302

  Fly   898 GGFVSVVKADNDDSPLGGGDGSNDHEQLPALQLQQHELQQIAGSLQQQHLVPHPHHEAIVLNQQH 962
            ..::...:...|:..|              .|..:||...           |...|..:|.....
  Rat   303 ELYLHFQEHSRDEQYL--------------CQFCEHETGD-----------PEDLHSHVVNEHAR 342

  Fly   963 RLVTIS 968
            ||:.:|
  Rat   343 RLIELS 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14442	NP_572342.1	PRK11675	<692..>709	CDD:183272	4/16 (25%)
Zfp639	NP_001074376.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..23
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	54..82		3/12 (25%)
		C2H2 Zn finger	235..255	CDD:275368	5/33 (15%)
		C2H2 Zn finger	262..283	CDD:275368	2/20 (10%)
		C2H2 Zn finger	291..307	CDD:275368	3/15 (20%)
		Interaction with CTNNA2. /evidence=ECO:0000250	371..455
		C2H2 Zn finger	376..397	CDD:275368
		C2H2 Zn finger	405..425	CDD:275368
		zf-C2H2_8	408..481	CDD:406359
		C2H2 Zn finger	433..454	CDD:275368
		C2H2 Zn finger	462..482	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342330
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930