DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14442 and ikzf4

DIOPT Version :9

Sequence 1:	NP_572342.1	Gene:	CG14442 / 31609	FlyBaseID:	FBgn0029893	Length:	1034	Species:	Drosophila melanogaster
Sequence 2:	XP_005162323.1	Gene:	ikzf4 / 566844	ZFINID:	ZDB-GENE-180319-1	Length:	572	Species:	Danio rerio

Alignment Length:	282	Identity:	56/282 - (19%)
Similarity:	86/282 - (30%)	Gaps:	94/282 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   507 PHKYAAKKQELQSDNDATVSAGGN-DNSGSVSLGHNETKVIVTTASG---------------EQK 555
            |.|:..:|....:.::|......| |..|.:.|.|.|.........|               ..:
Zfish   303 PQKFLGEKHMRLNISEAPYDLDPNPDKEGDLLLSHPEGDPAALAEMGGRFMRGPRGGSNDVDPSR 367

  Fly   556 LLKATPGQAQQLYNQF-PYLAT-FPNTTSSGNSTTSTTNVGHVGVVTAGTTTGAGGTTTTAYYPM 618
            .|:..|..|  ..::| |.::: :|:.|..|.....   .|.:.:..||...|.|
Zfish   368 SLRMPPHSA--CLSEFTPVISSVYPHITPLGQRLNC---AGGISMGLAGREAGEG---------- 417

  Fly   619 YHNGFQIGIGPNAVPPPFTPVNFANASGGNSPGQYNILAANPTLTVTGLGQQEQQQTGASSAAAP 683
             |...           |.|....|:.|.|                       .|..|...|.|..
Zfish   418 -HEDL-----------PSTRSRAASPSNG-----------------------YQDSTDTESMAEE 447

  Fly   684 QIVTT--PVG----RGRPRKNPLPSEEQLKVNSLLEQELNQMLSAPQLATSTPRRGRPLSQASQQ 742
            |.|.|  |.|    |||.|.:|..::|       ::.|.::....|   ...|.:..|.|..:::
Zfish   448 QCVITSAPPGNLNHRGRDRHSPSHAKE-------MDIEGDREKGVP---GGLPTKASPRSPLTRE 502

  Fly   743 HHQELSQIHVHSTADGDSRTPV 764
            ..|         ..||:.| ||
Zfish   503 AMQ---------VVDGEGR-PV 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14442	NP_572342.1	PRK11675	<692..>709	CDD:183272	6/16 (38%)
ikzf4	XP_005162323.1	C2H2 Zn finger	130..150	CDD:275368
		zf-H2C2_2	143..172	CDD:290200
		COG5048	<146..337	CDD:227381	8/33 (24%)
		zf-C2H2	161..183	CDD:278523
		C2H2 Zn finger	163..183	CDD:275368
		zf-H2C2_2	175..200	CDD:290200
		C2H2 Zn finger	191..211	CDD:275368
		C2H2 Zn finger	224..245	CDD:275368
		C2H2 Zn finger	519..539	CDD:275368
		C2H2 Zn finger	547..564	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582298
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930