Protein Alignment CG14442 and Zfp382

DIOPT Version :9

• Sequence 1: NP_572342.1
• Gene: CG14442 / 31609
• FlyBaseID: FBgn0029893
• Length: 1034
• Species: Drosophila melanogaster
• Sequence 2: NP_001074476.1
• Gene: Zfp382 / 233060
• MGIID: 3588204
• Length: 579
• Species: Mus musculus
• Alignment Length: 345
• Identity: 68/345 - (19%)
• Similarity: 112/345 - (32%)
• Gaps: 116/345 - (33%)

  Fly   689 PVGRGRPRKNPLPSEEQLKVNSLLEQELNQMLSAPQLATSTPRRGRPLSQASQQHHQELSQIHVH 753
            |.||.||...|.|.|| |:........||.|...|                     .....:.|.
Mouse     8 PRGRARPGLFPFPKEE-LRQGGSSPANLNAMSKGP---------------------VSFKDVTVD 50

  Fly   754 STADGDSRTPVLTPRRSGANKYETEEEKRIRLDKMA---AHQRAVRANETPEQRATRLQKLSERA 815
            .|.:...|   |.|           .:|.:..|.|.   .|..:|..:.|   :...::||.:..
Mouse    51 FTQEEWQR---LDP-----------AQKALYRDVMLENYCHFISVGFHIT---KPDMIRKLEQGE 98

  Fly   816 RLKRAQIRATENTDERKERLSKQAEYARMRRMRSHTPRSSSATSTEFRAKTEEEDECQDDDTSAE 880
            .|...:|..:::..|.:|.|.|.::|                           :|:........:
Mouse    99 ELWTERIFPSQSYLEEEEVLVKFSDY---------------------------QDKPPKSIVIIK 136

  Fly   881 HHMYESEAVSVTGTG---------------SDGGFVSVVK--ADNDDSP-LGGGDGSNDHEQLPA 927
            |.....|..||.|..               |||..:..:.  ...|.:| :|...||.:.|
Mouse   137 HKKLIKERSSVYGEALGKNRVVSKTLFEYKSDGKVLKNISEFISRDINPAMGKLGGSKEWE---- 197

  Fly   928 LQLQQHELQQIAGSLQQQHLVPHPHHEAIVLNQQ-HRLVT----ISQHQQQQLHQQQHPGFSK-- 985
                    ..|..|.|::      .|.|.:|::| .|.::    ::|||:.|:.:|:.. ::|
Mouse   198 --------GSILTSKQEK------THPASILHKQIGRALSSEWDLAQHQKTQIPEQRFE-YNKCD 247

  Fly   986 ---LQTVKDYANAAGGGGGG 1002
               |.|..::.:.....|||
Mouse   248 SSFLMTGVEFPHGRAHRGGG 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14442	NP_572342.1	PRK11675	<692..>709	CDD:183272	8/16 (50%)
Zfp382	NP_001074476.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37		12/29 (41%)
		Mediates interaction with TRIM28. /evidence=ECO:0000250	12..135		32/188 (17%)
		Represses transcription. /evidence=ECO:0000250	40..81		10/75 (13%)
		KRAB	42..102	CDD:214630	14/76 (18%)
		KRAB	42..81	CDD:279668	9/52 (17%)
		Represses transcription. /evidence=ECO:0000250	105..240		33/179 (18%)
		C2H2 Zn finger	303..319	CDD:275368
		Required for transcriptional repression activity, probably mediates sequence-specific DNA-binding. /evidence=ECO:0000250	325..579
		zf-C2H2	325..347	CDD:278523
		C2H2 Zn finger	327..347	CDD:275368
		zf-H2C2_2	339..364	CDD:290200
		C2H2 Zn finger	355..375	CDD:275368
		C2H2 Zn finger	383..403	CDD:275368
		COG5048	<411..562	CDD:227381
		C2H2 Zn finger	411..431	CDD:275368
		zf-H2C2_2	423..448	CDD:290200
		C2H2 Zn finger	439..459	CDD:275368
		zf-H2C2_2	452..474	CDD:290200
		C2H2 Zn finger	467..487	CDD:275368
		zf-H2C2_2	480..504	CDD:290200
		C2H2 Zn finger	495..515	CDD:275368
		C2H2 Zn finger	523..543	CDD:275368
		zf-C2H2	523..543	CDD:278523
		zf-H2C2_2	535..560	CDD:290200
		C2H2 Zn finger	551..571	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838531
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930