Protein Alignment CG14442 and IKZF2

DIOPT Version :9

• Sequence 1: NP_572342.1
• Gene: CG14442 / 31609
• FlyBaseID: FBgn0029893
• Length: 1034
• Species: Drosophila melanogaster
• Sequence 2: XP_011509104.1
• Gene: IKZF2 / 22807
• HGNCID: 13177
• Length: 533
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 92/540 - (17%)
• Similarity: 161/540 - (29%)
• Gaps: 186/540 - (34%)

  Fly   124 LGPTSSASSASITGASTTGHQQRWNESPEARQRRLARNAERMRERRQRESEEEY-RKRLLRNAEA 187
            |.|....|:.:|...|:|.:.|  :.||   ....:.|:.::    :.:|:||. ||.|.|..|.
Human    23 LSPEREHSNMAIDLTSSTPNGQ--HASP---SHMTSTNSVKL----EMQSDEECDRKPLSREDEI 78

  Fly   188 NRQRRQNESDIERAMRLVRNAARQRLRRAMESPDQRAKRLAKLAERMRMYRASETNDQRKLRLAE 252
               |..:|..                  ::|.|               :..:||..|.||::  |
Human    79 ---RGHDEGS------------------SLEEP---------------LIESSEVADNRKVQ--E 105

  Fly   253 MAARARQRIAN--------------------ESPEERKERLRKLNDYAKKVREKKKVLKHVVVHG 297
            :......|:.|                    .......||....|.......:|..:|:|:.:|.
Human   106 LQGEGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNLLRHIKLHS 170

  Fly   298 GSSSVVVSTPTSS--------------SSSTDQQH-------HHQQQQQQQQQQQQQQQQQQVLA 341
            |...  ...|..|              :.|..:.|       .::|:...::.:::.....|.::
Human   171 GEKP--FKCPFCSYACRRRDALTGHLRTHSVGKPHKCNYCGRSYKQRSSLEEHKERCHNYLQNVS 233

  Fly   342 VAAAAAAAA-----AANCTNEHTINLNQAT------TTATTTTTDEAG-----TPQPAEDQQ--- 387
            :.||....:     ..:|..:..|..|..:      .......|...|     |||....::
Human   234 MEAAGQVMSHHVPPMEDCKEQEPIMDNNISLVPFERPAVIEKLTGNMGKRKSSTPQKFVGEKLMR 298

  Fly   388 ------HLVTAAAYQQHQALAGVEYMGQGM-----FLAPGSLRPPMQLKQEPQTPQQQQITQQQL 441
                  |......|::...|.....|.|.:     :|...:|.|.|
Human   299 FSYPDIHFDMNLTYEKEAELMQSHMMDQAINNAITYLGAEALHPLM------------------- 344

  Fly   442 QQQHQRYTITGQQQQQVTAALLEGTEPGSIF--VQQIYGDEGGKGTAKLLQAHVPHFSIAGGQLE 504
              ||...|| .:....:::|..:...|..|.  :.:...|.              |.:...|.:.
Human   345 --QHPPSTI-AEVAPVISSAYSQVYHPNRIERPISRETADS--------------HENNMDGPIS 392

  Fly   505 LYPHKYAAKKQELQSDN---DATVSAGGNDNSGSVSLGH---------------NETKVIVTTAS 551
            |...|...:::|....|   |:|.|...:|:..|.. ||               .:.|.:.||
Human   393 LIRPKSRPQEREASPSNSCLDSTDSESSHDDHQSYQ-GHPALNPKRKQSPAYMKEDVKALDTT-- 454

  Fly   552 GEQKLLKATPGQAQQLYNQF 571
                  ||..|..:.:|..|
Human   455 ------KAPKGSLKDIYKVF 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14442	NP_572342.1	PRK11675	<692..>709	CDD:183272
IKZF2	XP_011509104.1	C2H2 Zn finger	121..141	CDD:275368	0/19 (0%)
		zf-H2C2_2	134..158	CDD:290200	3/23 (13%)
		COG5048	145..>214	CDD:227381	11/70 (16%)
		C2H2 Zn finger	149..169	CDD:275368	4/19 (21%)
		zf-H2C2_2	161..186	CDD:290200	6/26 (23%)
		C2H2 Zn finger	177..197	CDD:275368	2/19 (11%)
		C2H2 Zn finger	205..226	CDD:275368	1/20 (5%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930