Protein Alignment CG14442 and Ikzf2

DIOPT Version :10

• Sequence 1: NP_572342.1
• Gene: CG14442 / 31609
• FlyBaseID: FBgn0029893
• Length: 1034
• Species: Drosophila melanogaster
• Sequence 2: XP_011236806.1
• Gene: Ikzf2 / 22779
• MGIID: 1342541
• Length: 550
• Species: Mus musculus
• Alignment Length: 547
• Identity: 90/547 - (16%)
• Similarity: 159/547 - (29%)
• Gaps: 184/547 - (33%)

  Fly   127 TSSASSASITGASTTGHQQRWNE-SPEARQRRLARNAERMRERRQRESEEEYRKRLLRNAEANRQ 190
            |.:..:.:|.|..|:|.    || |||.....:|.:........|..|....       ...|..
Mouse    21 TLTMETDAIDGYITSGD----NELSPEGEHANMAIDLTSSTPNGQHASPSHM-------TSTNSV 74

  Fly   191 RRQNESDIERAMRLVRNAARQRLRR-----------AMESPDQRAKRLAKLAERMRMYRASETND 244
            :.:.:||.|        ..||.|.|           ::|.|               :..:||..|
Mouse    75 KLEMQSDEE--------CDRQPLSREDEIRGHDEGSSLEEP---------------LIESSEVAD 116

  Fly   245 QRKLRLAEMAARARQRIAN--------------------ESPEERKERLRKLNDYAKKVREKKKV 289
            .||::  ::......|:.|                    .......||....|.......:|..:
Mouse   117 NRKVQ--DLQGEGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQKGNL 179

  Fly   290 LKHVVVHGGSSSVVVSTPTSS--------------SSSTDQQH-------HHQQQQQQQQQQQQQ 333
            |:|:.:|.|...  ...|..|              :.|..:.|       .::|:...::.:::.
Mouse   180 LRHIKLHSGEKP--FKCPFCSYACRRRDALTGHLRTHSVGKPHKCNYCGRSYKQRSSLEEHKERC 242

  Fly   334 QQQQQVLAVAAAAAAAA-----AANCTNEHTINLNQ---------ATTTATTTTTD--EAGTPQP 382
            ....|.:::.||....:     ..:|..:..|..|.         |.....|....  ::.|||.
Mouse   243 HNYLQNVSMEAAGQVMSHHVPPMEDCKEQEPIMDNNISLVPFERPAVIEKLTANMGKRKSSTPQK 307

  Fly   383 AEDQQ---------HLVTAAAYQQHQALAGVEYMGQGM-----FLAPGSLRPPMQLKQEPQTPQQ 433
            ...::         |......|::...|.....|.|.:     :|...:|.|.|
Mouse   308 FVGEKLMRFSYPDIHFDMNLTYEKEAELMQSHMMDQAINNAITYLGAEALHPLM----------- 361

  Fly   434 QQITQQQLQQQHQRYTITGQQQQQVTAALLEGTEPGSIF--VQQIYGDEGGKGTAKLLQAHVPHF 496
                      ||...|| .:....:::|..:...|..|.  :.:...|.              |.
Mouse   362 ----------QHAPSTI-AEVAPVISSAYSQVYHPNRIERPISRETSDS--------------HE 401

  Fly   497 SIAGGQLELYPHKYAAKKQELQSDN---DATVSAGGNDN----SGSVSLG----------HNETK 544
            :...|.:.|...|...:::|....|   |:|.|...:|:    .|:.:|.          ..:.|
Mouse   402 NNMDGPISLIRPKSRPQEREASPSNSCLDSTDSESSHDDRQSYQGNPALNPKRKQSPAYMKEDVK 466

  Fly   545 VIVTTASGEQKLLKATPGQAQQLYNQF 571
            .:..|        ||..|..:.:|..|
Mouse   467 ALDAT--------KAPKGSLKDIYKVF 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14442	NP_572342.1	PRK12705	153..>282	CDD:237178	23/159 (14%)
Ikzf2	XP_011236806.1	C2H2 Zn finger	138..158	CDD:275368	0/19 (0%)
		zf-H2C2_2	151..175	CDD:463886	3/23 (13%)
		C2H2 Zn finger	166..186	CDD:275368	4/19 (21%)
		zf-H2C2_2	178..203	CDD:463886	6/26 (23%)
		C2H2 Zn finger	194..214	CDD:275368	2/19 (11%)
		zf-H2C2_2	210..231	CDD:463886	2/20 (10%)
		C2H2 Zn finger	222..243	CDD:275368	1/20 (5%)