Protein Alignment Pink1 and Pink1

DIOPT Version :9

• Sequence 1: NP_001027049.1
• Gene: Pink1 / 31607
• FlyBaseID: FBgn0029891
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_036020293.1
• Gene: Pink1 / 68943
• MGIID: 1916193
• Length: 592
• Species: Mus musculus
• Alignment Length: 599
• Identity: 194/599 - (32%)
• Similarity: 269/599 - (44%)
• Gaps: 150/599 - (25%)

  Fly   143 VSLASGSGV-LSKEDELEGVCWEIREAASRLQN-----AWNHDEISDTLDSK----FTIDDLEIG 197
            |.||.|.|: |.:|.:.||     |.|||..|.     ......:||.||::    |.::|..||
Mouse   100 VFLAFGLGLGLIEEKQAEG-----RRAASACQEIQAIFTQKTKRVSDPLDTRCWQGFRLEDYLIG 159

  Fly   198 PPIAKGCAAVVYAADFKKDVASDGASLHTDAQPQATPAFAPNSWSTHEMMSPLQNMSRFVH--NF 260
            ..|.|||.|.||                     :||....|            |::.:..|  ..
Mouse   160 QAIGKGCNAAVY---------------------EATMPTLP------------QHLEKAKHLGLI 191

  Fly   261 GGSVDNVFHYSQPSAASDFVGAQSREQDQRHHEQQQHQNQEQEQHQNQEPSSSAFNVTSPANSNI 325
            |...|.|..           ||..                      .|.|.:..|
Mouse   192 GKGPDVVLK-----------GADG----------------------EQAPGTPTF---------- 213

  Fly   326 NSSVDSYPLALKMMFNYDIQSNALSILRAMYKETVPARQRGMNEAADEWERLLQNQTVHLPR--- 387
                   |.|:|||:|....|::.:||..|.:|.|||.:..:   |.|:..:...::...|:
Mouse   214 -------PFAIKMMWNISAGSSSEAILSKMSQELVPASRVAL---AGEYGAVTYRRSRDGPKQLA 268

  Fly   388 -HPNIVCMFGFFCDEVRNFPDGHLLYPVAQPQRINPQGYGRNMSLYLLMKRYDHSLRGLLDSQDL 451
             ||||:.:|..|...|...|.....||...|....|:|.|...:|:|:||.|..:||..|:.|..
Mouse   269 PHPNIIRVFRAFTSSVPLLPGALADYPDMLPPHYYPEGLGHGRTLFLVMKNYPCTLRQYLEEQTP 333

  Fly   452 STRNRILLLAQMLEAVNHLSRHGVAHRDLKSDNVLIE-----LQD-------DAAPVLVLSDFGC 504
            |:|...::..|:||.|:||.:.|:|||||||||:|:|     ||:       |..|.||:|||||
Mouse   334 SSRLATMMTLQLLEGVDHLVQQGIAHRDLKSDNILVEWDSALLQERTPLHLMDGCPWLVISDFGC 398

  Fly   505 CLADKVHGLRLPYVSHDVDKGGNAALMAPEIFNTMPGPFAVLNYGKADLWACGALAYEIFGNRNP 569
            ||||:..|||||:.|..|::|||.:|||||:.....||.||::|.|||.||.||:||||||..||
Mouse   399 CLADQHVGLRLPFNSSSVERGGNGSLMAPEVSTAHSGPSAVIDYSKADTWAVGAIAYEIFGLANP 463

  Fly   570 FYSSSGGMARERGEMTLSLRNSDYRQDQLPPMSDACPPLLQQLVYNILNPNPSKRVSPDIAANVV 634
            ||          |:.:..|.:..|::.|||.|.::.||..::||.::|....|||.|..:||||:
Mouse   464 FY----------GQGSAHLESRSYQEAQLPEMPESVPPEARRLVRSLLQREASKRPSARLAANVL 518

  Fly   635 QLFLW-----APSNWLKAGGMPNSPEILQWLLSLTTKIMCEGRPQMGAGLMPVASCGNRRAYVEY 694
            .|.||     |..| ||...|      :.|||..:...:...|       :...||...:..:.:
Mouse   519 HLSLWGEHLLALKN-LKLDKM------IAWLLQQSAATLLADR-------LREKSCVETKLQMLF 569

  Fly   695 L--LICSFLARARL 706
            |  |.|..|.:|.|
Mouse   570 LANLECEALCQAAL 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pink1	NP_001027049.1	STKc_PINK1	328..639	CDD:270920	133/326 (41%)
Pink1	XP_036020293.1	STKc_PINK1	162..523	CDD:270920	123/378 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836985
Domainoid	1	1.000	211	1.000	Domainoid score	I2799
eggNOG	1	0.900	-	-		E1_KOG4158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	277	1.000	Inparanoid score	I2917
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008271
OrthoInspector	1	1.000	-	-		oto93126
orthoMCL	1	0.900	-	-		OOG6_109238
Panther	1	1.100	-	-	LDO	PTHR22972
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7349
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.750