Protein Alignment Pink1 and pink-1

DIOPT Version :9

• Sequence 1: NP_001027049.1
• Gene: Pink1 / 31607
• FlyBaseID: FBgn0029891
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_495017.1
• Gene: pink-1 / 173918
• WormBaseID: WBGene00017137
• Length: 641
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 129/491 - (26%)
• Similarity: 212/491 - (43%)
• Gaps: 149/491 - (30%)

  Fly   174 NAWNHDEISDTLDSKFTIDDLEIGPPIAKGCAAVVYAADFKKDVASDGASLHTDAQPQATPAFAP 238
            |:..::|...:.:....||..|.|..:.:||.|.||:|..          .::||:
 Worm   117 NSLRYNEDLKSTEWPNRIDSYEFGEFLGQGCNAAVYSARL----------ANSDAE--------- 162

  Fly   239 NSWSTHEMMSPLQNMSRFVHNFGGSVDNVFHYSQPSAASDFVGAQSREQDQRHHEQQQHQNQEQE 303
            :|.:||               :|...:.|
 Worm   163 SSGNTH---------------YGAGFNEV------------------------------------ 176

  Fly   304 QHQNQEPSSSAFNVTS--PANSNINSSVDSYPLALKMMFNYDIQSNA-LSILRAMYKETVPARQR 365
                       .|:.:  |..|.:  :...:|||:|:|||::...:. ..:|::|..|..|
 Worm   177 -----------TNILAEIPPVSKV--AQKKFPLAIKLMFNFEHDRDGDAHLLKSMGNELAP---- 224

  Fly   366 GMNEAADEWERLLQNQ--TVH-LP-RHPNIVCMFGFFCDEVRNFPDGHLLYP------------V 414
             ...||    :||..|  |.. || :|||:|.:...|.|.::..||....||            .
 Worm   225 -YPNAA----KLLNGQMGTFRPLPAKHPNVVRIQTAFIDSLKVLPDAIERYPDALHTARWYESIA 284

  Fly   415 AQPQRINPQGYGRNMSLYLLMKRYDHSLRGLLDSQDLSTRNR-----ILLLAQMLEAVNHLSRHG 474
            ::|:           ::|::|:||..:|.     :.:.||:|     .:::||:|||..:|.:|.
 Worm   285 SEPK-----------TMYVVMRRYRQTLH-----EYVWTRHRNYWTGRVIIAQLLEACTYLHKHK 333

  Fly   475 VAHRDLKSDNVLIELQ-DDAAPVLVLSDFGCCLADKVHGLRLPYVSHDVDKGGNAALMAPEIFNT 538
            ||.||:||||:|:|.. ||..|.||::||||.||  ....::.|.|.:|..||||...||||...
 Worm   334 VAQRDMKSDNILLEYDFDDEIPQLVVADFGCALA--CDNWQVDYESDEVSLGGNAKTKAPEIATA 396

  Fly   539 MPGPFAVLNYGKADLWACGALAYEIFGNRNPFYSSSGGMARERGEMTLSLRNSDYRQDQLPPMSD 603
            :||....:|:..||.||.|.|:||:....||||.              .|..:.|::.:||.:..
 Worm   397 VPGKNVKVNFEMADTWAAGGLSYEVLTRSNPFYK--------------LLDTATYQESELPALPS 447

  Fly   604 ACPPLLQQLVYNILNPNPSKRVSPDIAANVVQLFLW 639
            ....:.:.:::::|..:|::||.|:||||.:.|.|:
 Worm   448 RVNFVARDVIFDLLKRDPNERVKPNIAANALNLSLF 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pink1	NP_001027049.1	STKc_PINK1	328..639	CDD:270920	106/333 (32%)
pink-1	NP_495017.1	S_TKc	137..468	CDD:214567	116/454 (26%)
		STKc_PINK1	143..483	CDD:270920	122/463 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159226
Domainoid	1	1.000	136	1.000	Domainoid score	I3060
eggNOG	1	0.900	-	-		E1_KOG4158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008271
OrthoInspector	1	1.000	-	-		oto18861
orthoMCL	1	0.900	-	-		OOG6_109238
Panther	1	1.100	-	-	LDO	PTHR22972
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2724
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.770