Protein Alignment Fum2 and Fh1

DIOPT Version :10

• Sequence 1: NP_727109.2
• Gene: Fum2 / 31606
• FlyBaseID: FBgn0029890
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_034339.2
• Gene: Fh1 / 14194
• MGIID: 95530
• Length: 507
• Species: Mus musculus
• Alignment Length: 463
• Identity: 337/463 - (72%)
• Similarity: 389/463 - (84%)
• Gaps: 3/463 - (0%)

  Fly    42 FRTEKDTFGELKVPADKLYGAQTMRSKLNFPIGDIGERMPMPVIQAMGILKKACAEVNKDYGLDG 106
            ||.|.|||||||||.||.|||||:||.:||.||...||||:|||||.||||:|.||||::||||.
Mouse    47 FRVEFDTFGELKVPTDKYYGAQTVRSTMNFKIGGATERMPIPVIQAFGILKRAAAEVNQEYGLDP 111

  Fly   107 KVSDAVSCACDDVISGKLYKQGHFPLVIWQTGSGTQTNMNTNEVISNAAIKMMGGELGSKKPVHP 171
            |::.|:..|.|:|..|||  ..|||||:||||||||||||.||||||.||:|:||||||||||||
Mouse   112 KIASAIMKAADEVAEGKL--NDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHP 174

  Fly   172 NDHVNKSQSSNDTFPTAIHISVGMELNERLVPAVTHLRDALKSKSDEFKDIIKIGRTHLMDAVPL 236
            |||||||||||||||||:||:..:|:::.|:|.:..|.|||.:||.||..:|||||||..|||||
Mouse   175 NDHVNKSQSSNDTFPTAMHIAAAVEVHKVLLPGLQKLHDALSAKSKEFAQVIKIGRTHTQDAVPL 239

  Fly   237 TLGQEFSGYTQQLTNGLERIKGCLPRVYELALGGTAVGTGLNTRKGFAEKVAKRISELTCLPFVS 301
            |||||||||.||:...:.|||..:||:||||.||||||||||||.|||||||.:::.||.||||:
Mouse   240 TLGQEFSGYVQQVQYAMVRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVT 304

  Fly   302 APNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRLLGSGPRCGLGELMLPENEPGSSIMPGKV 366
            ||||||||||.||:||:.|.:||.|.||||||||||.||||||.|||||:|||||||||||||||
Mouse   305 APNKFEALAAHDALVELSGAMNTAACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKV 369

  Fly   367 NPTQCESMTMLCAQVMGNQVAVTIGGSNGHFELNVFKPLVVSNVLRSIRLLADGSMTFSKNCVEG 431
            ||||||:|||:.||||||.||||:||||||||||||||:::.|||.|.|||.|.|::|:.|||.|
Mouse   370 NPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTDNCVVG 434

  Fly   432 LQANKERIDKIMNESLMLVTALNPHIGYDKAALIAKTAHKNKTTLKEEALKTG-ITEEQFKEWVN 495
            :|||.|||:|:|||||||||||||||||||||.||||||||.:||||.|::.| :|.|||.|||.
Mouse   435 IQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVK 499

  Fly   496 PKEMLGPK 503
            ||:|||||
Mouse   500 PKDMLGPK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fum2	NP_727109.2	FumC	42..501	CDD:439884	333/459 (73%)
Fh1	NP_034339.2	FumC	46..505	CDD:439884	333/459 (73%)