Protein Alignment Fum1 and Fum4

DIOPT Version :10

• Sequence 1: NP_572339.1
• Gene: Fum1 / 31605
• FlyBaseID: FBgn0286222
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: NP_723527.1
• Gene: Fum4 / 318995
• FlyBaseID: FBgn0051874
• Length: 484
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 289/469 - (61%)
• Similarity: 372/469 - (79%)
• Gaps: 2/469 - (0%)

  Fly    28 RLASQEFRVESDTFGELKVPADKYYGAQTMRSQINFPIGGATERMPKPVVQAMGILKKAAAEVNK 92
            ||...:.|||.|:.|.:.:|.|:.:|.|||||.:.|||||..||||:|:::|:||:||:|||.||
  Fly    17 RLIVPDTRVEYDSMGAVHIPLDRMFGPQTMRSLMKFPIGGVEERMPRPLIKALGIVKKSAAETNK 81

  Fly    93 EFGLDSKVSEAISKAADDVISGKLYD-DHFPLVIWQTGSGTQSNMNVNEVISNRAIELLGGKLGS 156
            ...|:..:.:|||||.|||||||||| :||||||||.|||..:||||||||.|||||:|||::||
  Fly    82 IHCLEEHLCDAISKACDDVISGKLYDEEHFPLVIWQDGSGEHTNMNVNEVICNRAIEILGGQMGS 146

  Fly   157 KTPVHPNDHVNKSQSSNDTFPTAIHISVALELNNNLKPAIKTLHDALRAKSEEFKDIIKIGRTHT 221
            |.||.||:|||.:|||:|||.||:.|:||::|...|.|:::|..|.|..||.::.|:|||||||.
  Fly   147 KEPVDPNEHVNMAQSSHDTFSTAVRIAVAMQLQETLYPSLRTFIDLLGKKSNDWMDLIKIGRTHL 211

  Fly   222 MDAVPLTLGQEFSGYAQQLAYAQERIDACLPRVYELALGGTAVGTGLNTRKGFAEKCAAKIAELT 286
            ||||||:||||||||.|||...:.|:|..:.|:|:|.:|||:|||.::|:..::.:|..:|||||
  Fly   212 MDAVPLSLGQEFSGYQQQLVNGRTRLDCAMCRLYQLPMGGTSVGTKVDTKAEYSAQCIKRIAELT 276

  Fly   287 SLPFVTAPNKFEALAARDAMVEVHGVLNTIAVSLMKIANDIRFLGSGPRCGLGELSLPENEPGSS 351
            .||||.:||.||:::|.|.:||:||.|||||.|:|||||||||||||||||.|||.|||||||||
  Fly   277 FLPFVESPNFFESISACDCLVELHGELNTIAASVMKIANDIRFLGSGPRCGFGELHLPENEPGSS 341

  Fly   352 IMPGKVNPTQCESLTMLSAQVMGNQVAVTIGGSNGHFELNVFKPLIVSNVLRSIRLLSDGSRTFT 416
            ||||||||||||:::|:.||||||.|||::|||:|||:||.|.|:|.|||||||.||.||.::|.
  Fly   342 IMPGKVNPTQCEAMSMICAQVMGNHVAVSMGGSSGHFQLNTFMPMIASNVLRSITLLGDGMKSFC 406

  Fly   417 ANCVNGIQANRENIAKIMNESLMLVTALNPHIGYDKAAKIAKTAHKNGTTLKEEAINLGYLTEQQ 481
            .||:.||:.||..|..|:.|||||||||:|||||:::|.|||.||.|||||::||| |..:..:.
  Fly   407 TNCLEGIEPNRSKIGSIVKESLMLVTALSPHIGYERSAAIAKAAHHNGTTLEQEAI-LDGIQRED 470

  Fly   482 FNDWVRPEQMLGPK 495
            |.:||:|.:||||:
  Fly   471 FREWVQPSKMLGPE 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fum1	NP_572339.1	FumC	31..493	CDD:439884	284/462 (61%)
Fum4	NP_723527.1	Fumarase_classII	24..480	CDD:176465	283/456 (62%)