Protein Alignment Mcm6 and MCM5

DIOPT Version :10

• Sequence 1: NP_511065.1
• Gene: Mcm6 / 31603
• FlyBaseID: FBgn0025815
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_178812.1
• Gene: MCM5 / 815415
• AraportID: AT2G07690
• Length: 727
• Species: Arabidopsis thaliana
• Alignment Length: 755
• Identity: 236/755 - (31%)
• Similarity: 370/755 - (49%)
• Gaps: 130/755 - (17%)

  Fly    25 FQDFLEEFK-EDGEIKYTRPAASLESPDRCTLEVSFEDVEKYDQNLATAIIE---EYYHIYPFLC 85
            |::|:..|: |.....|..  |.|::|.|  |.|..||:..:|.:|.:.|..   :|..::....
plant    35 FKEFIRNFEIEQNCFPYRE--ALLDNPKR--LVVHLEDLLSFDSDLPSLIRSAPADYLPVFEKAA 95

  Fly    86 QSVSNYVKDRIGLKTQKDCYVAFTEVPTRHKVRDLTTSK-------------IGTLIRISGQVVR 137
            ..|..      |||.::.......|.|....|:.|.||:             |..|::|||..:.
plant    96 GEVLT------GLKMREANEGGVMEEPLTRDVQILLTSREDPVSMRLLGAQYISKLVKISGISIA 154

  Fly   138 THPVHPELVSGVFMCLDCQTEIRNVEQQFKFTNPTICRNPV--------CSNRKR---------- 184
            ...|..:......:|.:|           |.|....||..:        |.|..:
plant   155 ASRVKAKATYVFLVCKNC-----------KKTREVPCRPGLGGAIVPRSCDNIPQPGEEPCPLDP 208

  Fly   185 FMLDVEKSLFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVVPDVS 249
            :|:..::|.::|.|.:::||...::|.|.:||.:.:.:...||:|:..|.|....|
plant   209 WMVVPDRSQYVDQQTLKLQENPEDVPTGELPRNMLLSVDRHLVQTIVPGTRLTVMG--------- 264

  Fly   250 VLAGVGTRAENSSRHKPGEGMDGVTGLKALGMRELNYRMAFLACSVQATT---ARFGGTDLPMSE 311
             :..:...:.:|:.||           .|:.:|:...|:..|..:.:|::   |.|    .|..|
plant   265 -IYSIFQASSSSNSHK-----------GAVAIRQPYIRVVGLEDTNEASSRGPANF----TPDEE 313

  Fly   312 VTAEDMKKQMTDAEWHKIYEMSKDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAKTTTEKT 376
               |:.||            .:..:::|:|:.:.:.|||:|:::|||......|||..|:..:..
plant   314 ---EEFKK------------FADSQDVYKNICTKIAPSIFGHEDVKRAAACLLFGGSRKSLPDGV 363

  Fly   377 SLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFVIEAGAL 441
            .|||||||.::||||||||||||.|...:|.|:|||||.||||||||:|:||..:.:|.:|.||:
plant   364 KLRGDINVLLLGDPSTAKSQFLKFVEKTAPIAVYTSGKGSSAAGLTASVIRDSSTREFYLEGGAM 428

  Fly   442 MLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIARAGVRATLNARTSILAAANPINGRYDRSK 506
            :|||.|:.||||||||...|:|||||||||||||||:||:...||:|||:||||||.:||||..|
plant   429 VLADGGVVCIDEFDKMRPEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPPSGRYDDLK 493

  Fly   507 SLQQNIQLSAPIMSRFDLFFILVDECNEVVDYAIARKIVDLHSNIEE-SVERAYTREE--VLRYV 568
            :.|.||.|...|:|||||.||:.|......|..||..|:.:|::..: |.|...::|:  :.||:
plant   494 TAQDNIDLQTTILSRFDLIFIVKDIRKYSQDKEIASHIIRVHASANKFSDENTDSKEDNWLKRYI 558

  Fly   569 TFAR-QFKPVISQEAGHMLVENYGHLR----QRDTGTSGRSTWRITVRQLESMIRLSEAMAKLEC 628
            .:.| :..|.:|::|...|...|..:|    :|...|...:...|||||||:::||||::||:..
plant   559 QYCRARCHPRLSKDAAENLQRKYVTIRMDMKRRAHETGEAAPIPITVRQLEAIVRLSESLAKMRL 623

  Fly   629 SNRVLERHVKEAFRLLNKSIIRVEQPDIHLDDDEGLDMDDGIQHDIDMENNGAAANVDENNGMDT 693
            |:......|.:||:|.:.|.:...:        .|::....|..::..|...|...:....|:..
plant   624 SHEATPDDVDKAFKLFDTSTMDAAR--------SGINQQINITGEMANEIKQAETQIKRRMGIGA 680

  Fly   694 SASGAVQKKKFTLSFEDYKNLS--------TMLVLHMRAE 725
            ..|    :::.   .||...:.        .:|::|.|.|
plant   681 RLS----ERRL---IEDLARMGMNDSMVRRALLIMHQRGE 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm6	NP_511065.1	MCM_N	22..109	CDD:464206	21/87 (24%)
		MCM	113..649	CDD:475121	201/577 (35%)
		MCM6_C	702..816	CDD:465688	6/32 (19%)
MCM5	NP_178812.1	MCM_N	34..127	CDD:464206	25/101 (25%)
		MCM	131..644	CDD:475121	197/563 (35%)