Protein Alignment Mcm6 and Mcm9

DIOPT Version :9

• Sequence 1: NP_511065.1
• Gene: Mcm6 / 31603
• FlyBaseID: FBgn0025815
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_082106.3
• Gene: Mcm9 / 71567
• MGIID: 1918817
• Length: 1134
• Species: Mus musculus
• Alignment Length: 654
• Identity: 190/654 - (29%)
• Similarity: 325/654 - (49%)
• Gaps: 88/654 - (13%)

  Fly    23 KLFQDFLEEFKEDGEIKYTRPAASLESPDRCTLEVSFEDVEKYDQNLATAIIEEYYHIYP----- 82
            ::|:.::.|:.::..:...:     |..:.....|....:..::.|:.   |.:|:.::|
Mouse    11 QVFESYVSEYHKNDILLILK-----ERDEDAHYPVVVNAMSLFETNME---IGDYFTVFPNEVLT 67

  Fly    83 -----------FLCQSVSNYVKDRIGLKTQKDCYVAFTEVPT-RHKVRD--LTTSKIGTLIRISG 133
                       .:.||    :.:..||..:::.:...:.:|. ...||:  ..|..:|..:.::|
Mouse    68 VFDSALRRSALAILQS----LPETEGLSMKQNLHARISGLPVCPELVREHIPKTKDVGHFLSVTG 128

  Fly   134 QVVRTHPVHPELVSGVFMCLDCQTEI---RNVEQQFKFTNPTICRNPVCSNRKRF--MLDVEKS- 192
            .|:||..|........:||..|:...   .:.||.:.|:.|:.|.:....:..:|  :.|:..|
Mouse   129 TVIRTSLVKVLEFERDYMCNKCKHVFMVEADFEQYYTFSRPSSCPSLASCDSSKFSCLSDLSSSP 193

  Fly   193 -LFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVVPDVSVLAGVGT 256
             ...|:|:|:|||....|..|.|||::::||..:||::.::||.....|.::
Mouse   194 ARCRDYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGVVM------------- 245

  Fly   257 RAENSSRHKPGEGMDGVTGLKALGMRELNYRMAFL--ACSVQATTARFGGTDLPMSEVTAEDMKK 319
                 .|.||.:             |::...:..:  |..||....:..|.      |..||.:|
Mouse   246 -----QRWKPFQ-------------RDVRCEVEIVLKANYVQVNNEQSSGM------VMDEDTRK 286

  Fly   320 QMTDAEWHKIYEMSKDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAKTTTEKTSLRGDINV 384
            :..|...|...:....||   .:::||.|.::|...||..:.:...||:.:|....|.:||:.::
Mouse   287 EFEDFWEHYKSDPFAGRN---EILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAAGTRVRGESHL 348

  Fly   385 CIVGDPSTAKSQFLKQVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGIC 449
            .:||||.|.||||||..:..:||::.|:|..|::||||...|:|  |.::.:|||||:|||.|:|
Mouse   349 LLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKD--SGEWNLEAGALVLADAGLC 411

  Fly   450 CIDEFDKMDQRDQVAIHEAMEQQTISIARAGVRATLNARTSILAAANPINGRYDRSKSLQQNIQL 514
            |||||:.:.:.|:.:|||||||||||:|:||:...||.||:||||.|| .|:||..:|:..||.|
Mouse   412 CIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQYDPKESVSVNIAL 475

  Fly   515 SAPIMSRFDLFFILVDECNEVVDYAIARKIVDLHSNIEESVERAYTREEVLRYVTFARQFKPVIS 579
            .:|::|||||..:|:|..||..|..|:..|:: :.......|..::.|::..|....|...|.:|
Mouse   476 GSPLLSRFDLVLVLLDTRNEDWDRIISSFILE-NKGYPSKSENLWSMEKMKTYFCLIRNLHPTLS 539

  Fly   580 QEAGHMLVENYGHLRQRDTGTSGRSTWRITVRQLESMIRLSEAMAKLECSNRVLERHVKEAFRLL 644
            :.:..:|:..|...||.|:    |:..|.|:|.|||:|||:||.|:|...:.|.......|..::
Mouse   540 EVSNQVLLRYYQMQRQSDS----RNAARTTIRLLESLIRLAEAHARLMFRSAVTLEDAVTAVSVM 600

  Fly   645 NKSI 648
            ..|:
Mouse   601 ESSM 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm6	NP_511065.1	MCM_N	25..109	CDD:379644	12/99 (12%)
		MCM	113..649	CDD:214631	177/548 (32%)
		MCM6_C	702..816	CDD:375690
Mcm9	NP_082106.3	Mcm2	10..605	CDD:224162	190/654 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	659..1101
		DUF4045	<739..>1004	CDD:330572

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920