Protein Alignment Mcm6 and mcm6l

DIOPT Version :10

• Sequence 1: NP_511065.1
• Gene: Mcm6 / 31603
• FlyBaseID: FBgn0025815
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_001020704.1
• Gene: mcm6l / 564982
• ZFINID: ZDB-GENE-050913-141
• Length: 824
• Species: Danio rerio
• Alignment Length: 818
• Identity: 507/818 - (61%)
• Similarity: 635/818 - (77%)
• Gaps: 15/818 - (1%)

  Fly    11 LRVKDEVGIRAQKLFQDFLEEFKE-DGEIKYTRPAASLESPDRCTLEVSFEDVEKYDQNLATAII 74
            :.|:||:..:.||||.:|||||:: :|:..|...|..|..|:|.||.|||.::|.|:|.|||.|.
Zfish    10 VHVRDELSEKCQKLFLEFLEEFQDKNGDALYLSDAQELIRPERNTLTVSFSNIEHYNQQLATTIQ 74

  Fly    75 EEYYHIYPFLCQSVSNYVKDRIGLKTQKDCYVAFTEVPTRHKVRDLTTSKIGTLIRISGQVVRTH 139
            ||||.:|||||::|.::.:|...:...|:.||||:|.|:|.|:|:|:|.:||||:||||||||||
Zfish    75 EEYYRVYPFLCRAVRHFARDHGNIPPSKEFYVAFSEFPSRQKIRELSTVRIGTLLRISGQVVRTH 139

  Fly   140 PVHPELVSGVFMCLDCQTEIRNVEQQFKFTNPTICRNPVCSNRKRFMLDVEKSLFLDFQKIRIQE 204
            |||||||||.|:|||||:.|::||||||:|.||||:||||:||:|||||..||.|:||||.||||
Zfish   140 PVHPELVSGTFLCLDCQSVIKDVEQQFKYTQPTICKNPVCANRRRFMLDTNKSRFVDFQKGRIQE 204

  Fly   205 TQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVVPDVSVLAGVGTRAENSSRHKPGEG 269
            ||||||||.|||:||:|||:|.|||.|||||.||||||:||||||.:|..|||||.|||....||
Zfish   205 TQAELPRGSIPRSVEVILRAEAVETAQAGDRCDFTGTLVVVPDVSAMALAGTRAETSSRVTGKEG 269

  Fly   270 M--DGVTGLKALGMRELNYRMAFLACSVQATTARFGGTDLPMSEVTAEDMKKQMTDAEWHKIYEM 332
            .  ||:.||||||:|||:||:||||..|..|..||||.:|...:.|||.:|.|||..||.|::||
Zfish   270 FETDGIQGLKALGVRELSYRLAFLANYVAPTNPRFGGKELRQEDQTAESVKNQMTVLEWEKVFEM 334

  Fly   333 SKDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAKTTTEKTSLRGDINVCIVGDPSTAKSQF 397
            |:|:|||.||.:||||:|:||||:||||||..||||||||.|.|||||||||||||||||:||||
Zfish   335 SQDKNLYHNLCTSLFPTIHGNDEIKRGILLMLFGGVAKTTMEGTSLRGDINVCIVGDPSTSKSQF 399

  Fly   398 LKQVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGICCIDEFDKMDQRDQ 462
            ||.|.||:|||:|||||||||||||||||:||||.:||||||||||||||:||||||||||.:||
Zfish   400 LKHVEDFAPRAVYTSGKASSAAGLTAAVVKDEESHEFVIEAGALMLADNGVCCIDEFDKMDLKDQ 464

  Fly   463 VAIHEAMEQQTISIARAGVRATLNARTSILAAANPINGRYDRSKSLQQNIQLSAPIMSRFDLFFI 527
            ||||||||||||||.:|||:||||||||||||||||:|||:|:|||:||:.:|||||||||||||
Zfish   465 VAIHEAMEQQTISITKAGVKATLNARTSILAAANPIDGRYNRAKSLKQNVNMSAPIMSRFDLFFI 529

  Fly   528 LVDECNEVVDYAIARKIVDLHSNIEESVERAYTREEVLRYVTFARQFKPVISQEAGHMLVENYGH 592
            ||||||||.||||||:|||||:...|||||.|:.:|:.||:.|||||:|.|:.||...:|:.|..
Zfish   530 LVDECNEVTDYAIARRIVDLHARNVESVERVYSTDEIQRYILFARQFQPKITVEAQEFVVDQYKR 594

  Fly   593 LRQRDTGTSGRSTWRITVRQLESMIRLSEAMAKLECSNRVLERHVKEAFRLLNKSIIRVEQPDIH 657
            |||||.|.:.:|.|||||||||||:||||.||:|.||:.|..:||||||||||||||||:.|||:
Zfish   595 LRQRDGGGTTKSAWRITVRQLESMLRLSEGMARLYCSDEVQPKHVKEAFRLLNKSIIRVDSPDIN 659

  Fly   658 LD---DDEGL-DMDDGIQHDIDMEN----NGAAANVDENNGMDTSASGAVQKKKFTLSFEDYKNL 714
            .|   |::.: |.::....:.:.:|    ||.|....|.:..:.....|..|....:||.:||.:
Zfish   660 FDQEHDEDNINDQNELFGKETEGQNGGDVNGHAVEDMETDQTEKPEKPAAAKPALRMSFAEYKRV 724

  Fly   715 STMLVLHMRAEEARCEVEGNDTGIKRSNVVTWYLEQVADQIESEDELISRKNLIEKLIDRLIYHD 779
            |.:|||||:..|...|    |:.:|:|.::.|||:::..:|:||.||:::|||||:::.|||..|
Zfish   725 SNLLVLHMQKMEQLDE----DSSLKKSELINWYLKEIESEIDSEAELVAKKNLIERVLYRLINFD 785

  Fly   780 QVIIPLKTSTLKPRIQVQKDFVEEDDPLLVVHPNYVVE 817
            .:||.|..:.||...:..::.|.||||.|||.|||::|
Zfish   786 HIIIELTKTGLKKISEDGEEPVSEDDPFLVVDPNYILE 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm6	NP_511065.1	MCM_N	22..109	CDD:464206	42/87 (48%)
		MCM	113..649	CDD:475121	393/537 (73%)
		MCM6_C	702..816	CDD:465688	48/113 (42%)
mcm6l	NP_001020704.1	MCM_N	21..109	CDD:464206	42/87 (48%)
		MCM	116..651	CDD:475121	392/534 (73%)
		MCM6_C	712..820	CDD:465688	46/111 (41%)