Protein Alignment Mcm6 and Mcm5

DIOPT Version :9

• Sequence 1: NP_511065.1
• Gene: Mcm6 / 31603
• FlyBaseID: FBgn0025815
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_524308.2
• Gene: Mcm5 / 41296
• FlyBaseID: FBgn0017577
• Length: 733
• Species: Drosophila melanogaster
• Alignment Length: 678
• Identity: 223/678 - (32%)
• Similarity: 344/678 - (50%)
• Gaps: 84/678 - (12%)

  Fly     5 DAQVGQLRVKDEVGIRAQKLFQDFLEEFKEDGEI-KYTRPAASLESPDRCTLEVSFEDVEKYDQN 68
            |||:....||        |.:::|:..|.|:... ||...........|..||:..||:..:|:.
  Fly    22 DAQINLQAVK--------KKYKEFIRTFNEENFFYKYRDTLKRNYLNGRYFLEIEMEDLVGFDET 78

  Fly    69 LATAIIE---EYYHIYPFLCQSVSNYVKDRIGL------KTQKDCYVAFTEVPTRHKVRDLTTSK 124
            ||..:.:   |:..|:    :..:..|.|.|..      :...|..:..:.......:|.|.:..
  Fly    79 LADKLNKQPTEHLEIF----EEAAREVADEITAPRPEHEEHMHDIQILLSSNANPTNIRQLKSDC 139

  Fly   125 IGTLIRISGQVVRTHPVHPELVSGVFMCLDCQTEIRNVEQQFKFTNPTI--------CR-----N 176
            :..|::|:|.:|....:..:.......||.|.|.|.|::     .||.:        |.     .
  Fly   140 VSKLVKIAGIIVAASGISAKATRMSIQCLSCSTVIPNLK-----VNPGLEGYALPRKCNTEQAGR 199

  Fly   177 PVCSNRKRFMLDVEKSLFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGT 241
            |.|.....|::. :|...:|||.:::||....:|:|.|||.:::.....|.|.|..|:|
  Fly   200 PKCPLDPFFIMP-DKCKCVDFQTLKLQELPDFVPQGEIPRHLQLFCDRSLCERVVPGNR------ 257

  Fly   242 LIVVPDVSVLAGVGTRAENSSRHKPGEGMDGVTGLKALGMRELNYRMAFLACSVQATTARFGGTD 306
             :::..:..:..||..:....|.|      .|.|::|..||       .:..:|.:..|   |..
  Fly   258 -VLIQGIYSIRKVGKPSRRDGREK------AVVGVRAPYMR-------VVGITVDSEGA---GAI 305

  Fly   307 LPMSEVTAEDMKKQMTDAEWHKIYEMSKDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAKT 371
            ...|.:|        :|.|.| ...|:...::|:.|..||.|||:|:.::|:.|....|||..|.
  Fly   306 SRYSNIT--------SDEEEH-FRRMAASGDIYERLSQSLAPSIFGSRDIKKAITCMLFGGSRKR 361

  Fly   372 TTEKTSLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFVI 436
            ..:....||||||.::|||.|||||.||.|...:|.|:|||||.||||||||:|::|.::.:||:
  Fly   362 LPDGLCRRGDINVLLLGDPGTAKSQLLKFVEKVAPIAVYTSGKGSSAAGLTASVMKDPQTRNFVM 426

  Fly   437 EAGALMLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIARAGVRATLNARTSILAAANPINGR 501
            |.||::|||.|:.||||||||.:.|:|||||||||||||||:||:..|||:|.|:|||||.|.||
  Fly   427 EGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSIFGR 491

  Fly   502 YDRSKSLQQNIQLSAPIMSRFDLFFILVDECNEVVDYAIARKIVDLHSNIEESVERAYTREEV-- 564
            :|.:|. ::||.....|:||||:.||:.|..:|..|..:|:.|:::|.:..:|........|:
  Fly   492 WDDTKG-EENIDFMPTILSRFDMIFIVKDIHDESRDITLAKHIINVHLSSNKSAPSEPAEGEISL 555

  Fly   565 ---LRYVTFAR-QFKPVISQEAGHMLVENYGHLR----QRDTGTSGRSTWRITVRQLESMIRLSE 621
               .:|:.:.| ...|.:|:.||..|...|..:|    |::..:..|.:..|||||||::||:||
  Fly   556 STFKKYIHYCRTHCGPRLSEAAGEKLKSRYVLMRSGAGQQEKASDKRLSIPITVRQLEAVIRISE 620

  Fly   622 AMAKLECSNRVLERHVKEAFRLLNKSII 649
            ::||:.......:.||.||.||...|.:
  Fly   621 SLAKIRLQPFATDEHVNEALRLFQVSTL 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm6	NP_511065.1	MCM_N	25..109	CDD:379644	19/93 (20%)
		MCM	113..649	CDD:214631	198/558 (35%)
		MCM6_C	702..816	CDD:375690
Mcm5	NP_524308.2	MCM_N	31..124	CDD:405270	21/104 (20%)
		MCM	128..648	CDD:214631	198/558 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469739
Domainoid	1	1.000	52	1.000	Domainoid score	I661
eggNOG	1	0.900	-	-		E1_COG1241
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D15169at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11630
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850