Protein Alignment Mcm6 and Mcm7

DIOPT Version :10

• Sequence 1: NP_511065.1
• Gene: Mcm6 / 31603
• FlyBaseID: FBgn0025815
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_523984.1
• Gene: Mcm7 / 39014
• FlyBaseID: FBgn0020633
• Length: 720
• Species: Drosophila melanogaster
• Alignment Length: 750
• Identity: 230/750 - (30%)
• Similarity: 367/750 - (48%)
• Gaps: 113/750 - (15%)

  Fly    28 FLEEF---KEDG--EIKYTRPAASLESPDRCTLEVSFEDVEKYDQNLATAIIE---EYYHIY-PF 83
            ||.||   .:||  |..|......|...::..:.:..:|:.:::::||.|:::   .|..|: ..
  Fly    16 FLSEFCKCDDDGKKEFVYGSQLVKLAHREQVLITIDLDDLAEFNESLAEAVVDNCRRYTSIFSDV 80

  Fly    84 LCQSVSNYVKDRIGLKTQKDCY---------------------------------VAFTEVPTR- 114
            :.:.:.:|.:..:..|...|.|                                 |.|..:.|.
  Fly    81 IAELLPSYKQQEVHAKDALDVYIEHRLMMESRTRNPMEQRDERNSFPSELMKRFEVGFKPLSTEK 145

  Fly   115 -HKVRDLTTSKIGTLIRISGQVVRTHPVHPELVSGVFMCLDCQTEIRNVEQQFKFTNPTICRNPV 178
             |.:|::....||.|:.:.|.|.|...|.|.:|...:.|..|.:|.........||....|.:..
  Fly   146 AHSIREVKAQHIGKLVTVRGIVTRCTEVKPMMVVATYTCDRCGSETYQPVNSLSFTPVHDCPSDD 210

  Fly   179 CSNRK---RFMLDVEKSLFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTG 240
            |...|   |..|....|.|:.||::::||...::|.|.|||::.|:.|.|:....|.||..
  Fly   211 CRVNKAGGRLYLQTRGSKFVKFQEVKMQEHSDQVPVGHIPRSMTIMCRGEVTRMAQPGDHI---- 271

  Fly   241 TLIVVPDVSVLAGVGTRAENSSRHKPGEGMDGVTGLKALGMRELNYRMAFLACSVQATTARFGGT 305
                     |::||......:...:..:|:...|.|:|..:..:|..
  Fly   272 ---------VVSGVFLPLMRTGFAQMIQGLLSETFLQAHRIICINKN------------------ 309

  Fly   306 DLPMSEVTAEDMKKQMTDAEWHKIYEMSKDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAK 370
                .|::.:|  .::|..|   :.|:::| :.|:.|.:||.|.|||:.:||:.:||...|||.|
  Fly   310 ----DEISDKD--AELTPEE---LEELAQD-DFYERLATSLAPEIYGHLDVKKALLLLLVGGVDK 364

  Fly   371 TTTEKTSLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFV 435
             ..:...:||:||:|::|||..||||.|..:|..:.|:.||:|:.||..||||||::|..:.:..
  Fly   365 -RPDGMKIRGNINICLMGDPGVAKSQLLGYISRLAVRSQYTTGRGSSGVGLTAAVMKDPLTGEMT 428

  Fly   436 IEAGALMLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIARAGVRATLNARTSILAAANPING 500
            :|.|||:|||.|:|||||||||..:|:.||||.|||||||||:||:..|||||.||||||||..|
  Fly   429 LEGGALVLADQGVCCIDEFDKMADQDRTAIHEVMEQQTISIAKAGIMTTLNARVSILAAANPAFG 493

  Fly   501 RYDRSKSLQQNIQLSAPIMSRFDLFFILVDECNEVVDYAIARKIVDLHSNIEESVER--AYTREE 563
            ||:..::::|||||.|.::|||||.:::.|:.:...|..:|:.|..:||:.::...|  |.....
  Fly   494 RYNPRRTVEQNIQLPAALLSRFDLLWLIQDKPDRDNDLRLAKHITYVHSHSKQPPTRVKALDMNL 558

  Fly   564 VLRYVTFARQFKPVISQEAGHMLVENYGHLR-----QRD-TGTSGRSTWRITVRQLESMIRLSEA 622
            :.||:...::..|.|..|....:|..|..||     |:| |.||.|:        |..::|||.|
  Fly   559 MRRYINLCKRKNPTIPDELTDYIVGAYVELRREARNQKDMTFTSARN--------LLGILRLSTA 615

  Fly   623 MAKLECSNRVLERHVKEAFRLLNKSIIRVEQPDIHLDDDEG--LDMDDGIQHDI-DMENNGAAAN 684
            :|:|..|:.|.:..|.||.|||..|...:.|  || :..:|  .:..|.|...: ::..:|.|..
  Fly   616 LARLRLSDSVEKDDVAEALRLLEMSKDSLNQ--IH-EHQKGHVPNTSDRIFAIVRELAGSGKAVK 677

  Fly   685 VDENNGMDTSASGAVQKKKFTLSFEDYKNLSTMLV 719
            :.:.  ||...:...:..:.....:||:.|:...|
  Fly   678 ISDI--MDRCTTKGFKPDQVDKCIDDYEELNVWQV 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm6	NP_511065.1	MCM_N	22..109	CDD:464206	20/122 (16%)
		MCM	113..649	CDD:475121	195/548 (36%)
		MCM6_C	702..816	CDD:465688	3/17 (18%)
Mcm7	NP_523984.1	MCM_N	10..103	CDD:464206	18/86 (21%)
		MCM	145..641	CDD:475121	193/545 (35%)