Protein Alignment Mcm6 and Mcm6

DIOPT Version :10

• Sequence 1: NP_511065.1
• Gene: Mcm6 / 31603
• FlyBaseID: FBgn0025815
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_058983.1
• Gene: Mcm6 / 29685
• RGDID: 61967
• Length: 821
• Species: Rattus norvegicus
• Alignment Length: 817
• Identity: 513/817 - (62%)
• Similarity: 639/817 - (78%)
• Gaps: 26/817 - (3%)

  Fly    13 VKDEVGIRAQKLFQDFLEEFK-EDGEIKYTRPAASLESPDRCTLEVSFEDVEKYDQNLATAIIEE 76
            |:|||..:.||||.||||||: .||||||.:.|..|..|:|.||.|||.|:|:::|.|:|.|.||
  Rat    18 VRDEVAEKCQKLFLDFLEEFQGSDGEIKYLQFAEELIRPERNTLVVSFADLEQFNQQLSTTIQEE 82

  Fly    77 YYHIYPFLCQSVSNYVKDRIGLKTQKDCYVAFTEVPTRHKVRDLTTSKIGTLIRISGQVVRTHPV 141
            :|.:||:||:::..:||||..:...||.||||.::|||||:|:||:|:||.|.||||||||||||
  Rat    83 FYRVYPYLCRALKTFVKDRKEIPFAKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPV 147

  Fly   142 HPELVSGVFMCLDCQTEIRNVEQQFKFTNPTICRNPVCSNRKRFMLDVEKSLFLDFQKIRIQETQ 206
            |||||||.|:||||||.|::||||||:|.|:|||||||:|||||:||..||.|:||||:||||||
  Rat   148 HPELVSGTFLCLDCQTVIKDVEQQFKYTQPSICRNPVCANRKRFLLDTNKSRFVDFQKVRIQETQ 212

  Fly   207 AELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTLIVVPDVSVLAGVGTRAENSSRHKPGEG-- 269
            ||||||.|||::|::||:|.||:.|||||.|||||||||||||.|:..|.|||.:||....:|
  Rat   213 AELPRGSIPRSLEVVLRAEAVESAQAGDRCDFTGTLIVVPDVSKLSTPGARAETNSRVSGADGYE 277

  Fly   270 MDGVTGLKALGMRELNYRMAFLACSVQATTARFGGTDLPMSEVTAEDMKKQMTDAEWHKIYEMSK 334
            .:|:.||:|||:|:|:||:.||||.|..|..||||.:|...|.|||.:|.|||..||.|::|||:
  Rat   278 TEGIRGLRALGVRDLSYRLVFLACYVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEMSQ 342

  Fly   335 DRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAKTTTEKTSLRGDINVCIVGDPSTAKSQFLK 399
            |:|||.||.:||||:|:||||||||:||..||||.|||.|.||||||||||||||||||||||||
  Rat   343 DKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLK 407

  Fly   400 QVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGICCIDEFDKMDQRDQVA 464
            .|.:|||||:||||||||||||||||||||||.:||||||||||||||:||||||||||.|||||
  Rat   408 HVDEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDMRDQVA 472

  Fly   465 IHEAMEQQTISIARAGVRATLNARTSILAAANPINGRYDRSKSLQQNIQLSAPIMSRFDLFFILV 529
            ||||||||||||.:|||:|||||||||||||||::|.|||||||:|||.||||||||||||||||
  Rat   473 IHEAMEQQTISITKAGVKATLNARTSILAAANPVSGHYDRSKSLKQNINLSAPIMSRFDLFFILV 537

  Fly   530 DECNEVVDYAIARKIVDLHSNIEESVERAYTREEVLRYVTFARQFKPVISQEAGHMLVENYGHLR 594
            ||||||.||||||:||||||.||||::|.|:.:::.||:.|||||||.||:|:...:||.|..||
  Rat   538 DECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKRLR 602

  Fly   595 QRDTGTSGRSTWRITVRQLESMIRLSEAMAKLECSNRVLERHVKEAFRLLNKSIIRVEQPDIHLD 659
            |||.....:|:||||||||||||||||:||::.|.:.|..:|||||||||||||||||.||::||
  Rat   603 QRDGSGITKSSWRITVRQLESMIRLSESMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLD 667

  Fly   660 DDEGLDMD-----DGIQHDIDMENNGAAANVDENNGMDTSASGA----VQKKKFTLSFEDYKNLS 715
            .:|.:.|:     .||        ||.|.:....||.:.|...|    |.|....|.|.:|..:|
  Rat   668 QEEEIQMETDEGPGGI--------NGHADSPAPVNGFNGSGEDASQETVPKPSLRLGFAEYCRIS 724

  Fly   716 TMLVLHMRAEEARCEVEGNDTGIKRSNVVTWYLEQVADQIESEDELISRKNLIEKLIDRLIYHDQ 780
            .::|||:|    :.|.|.:::.:|||.:|.|||:::..:|:||:|||::|.:|||::.||.::|.
  Rat   725 NLIVLHLR----KMEEEEDESALKRSELVNWYLKEIESEIDSEEELINKKRIIEKVVHRLTHYDH 785

  Fly   781 VIIPLKTSTLKPRIQVQKDFVEEDDPLLVVHPNYVVE 817
            |:|.|..:.||...:..:.:  |:||.|||:|||::|
  Rat   786 VLIELTQAGLKGSSEGSESY--EEDPYLVVNPNYLLE 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm6	NP_511065.1	MCM_N	22..109	CDD:464206	47/87 (54%)
		MCM	113..649	CDD:475121	393/537 (73%)
		MCM6_C	702..816	CDD:465688	44/113 (39%)
Mcm6	NP_058983.1	MCM_N	27..116	CDD:464206	48/89 (54%)
		MCM	119..657	CDD:475121	395/539 (73%)
		MCM6_C	711..817	CDD:465688	41/105 (39%)