Protein Alignment Mcm6 and Mcm5

DIOPT Version :9

• Sequence 1: NP_511065.1
• Gene: Mcm6 / 31603
• FlyBaseID: FBgn0025815
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: XP_038953490.1
• Gene: Mcm5 / 291885
• RGDID: 1306616
• Length: 734
• Species: Rattus norvegicus
• Alignment Length: 675
• Identity: 211/675 - (31%)
• Similarity: 333/675 - (49%)
• Gaps: 77/675 - (11%)

  Fly     6 AQVGQLRVKDEVGIRAQKLFQDFLEEFKEDGE-----IKYTRPAASLESPDRCTLEVSFEDVEKY 65
            |:.||.|..     ..||.|::||.:::...:     .||........:.....:||..||:..:
  Rat    21 AEEGQARKS-----HLQKRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASF 80

  Fly    66 DQNLATAIIEEYYHIYPF----LCQSVSNYVKDRI------GLKTQKDCYVAFTEVPTRHKVRDL 120
            |:.||     :|.:..|.    |.:..:..|.|.:      |.:..:|..|......:...:|.|
  Rat    81 DEELA-----DYLYKQPAEHLQLLEEAAKEVADEVTRPRPAGDELLQDIQVMLKSDASPSSIRIL 140

  Fly   121 TTSKIGTLIRISGQVVRTHPVHPELVSGVFMCLDCQTEIRNVEQQ---FKFTNPTICR-----NP 177
            .:..:..|::|.|.::....|..:.......|..|...:.|:..:   ..:..|..|.     .|
  Rat   141 KSDMMSHLVKIPGIIISASAVRAKATRISIQCRSCHNTLTNIAMRPGLEGYALPRKCNMDQAGRP 205

  Fly   178 VCSNRKRFMLDVEKSLFLDFQKIRIQETQAELPRGCIPRAVEIILRSELVETVQAGDRYDFTGTL 242
            .|.....|::. :|...:|||.:::||....:|.|.:||.:::.....|.:.|..|:|....|..
  Rat   206 KCPLDPYFIMP-DKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIY 269

  Fly   243 IVVPDVSVLAGVGTRAENSSRHKPGEGMDGVTGLKALGMRELNYRMAFLACSVQATTARFGGTDL 307
            .:               ......|.:|.|.|    .:|:|....|:..:......:...|.|:..
  Rat   270 SI---------------KKFGMNPSKGRDRV----GVGIRSSYIRVLGIQVDTDGSGRSFAGSVS 315

  Fly   308 PMSEVTAEDMKKQMTDAEWHKIYEMSKDRNLYQNLISSLFPSIYGNDEVKRGILLQQFGGVAKTT 372
            |..|   |:.::            ::...|:|:.:..|:.|||:|..::|:.|....|||..|..
  Rat   316 PQEE---EEFRR------------LAALPNIYELVSRSVSPSIFGGMDMKKAIACLLFGGSRKRL 365

  Fly   373 TEKTSLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAIYTSGKASSAAGLTAAVVRDEESFDFVIE 437
            .:..:.|||||:.::|||.|||||.||.|...||..:|||||.||||||||:|:||..|.:|::|
  Rat   366 PDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVIRDPSSRNFIME 430

  Fly   438 AGALMLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIARAGVRATLNARTSILAAANPINGRY 502
            .||::|||.|:.||||||||.:.|:|||||||||||||||:||:..|||:|.|:|||||.:.||:
  Rat   431 GGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRW 495

  Fly   503 DRSKSLQQNIQLSAPIMSRFDLFFILVDECNEVVDYAIARKIVDLHSNI---EESVERAYTREEV 564
            |.:|. :.||.....|:||||:.||:.||.||..|..:|:.::.||.:.   .::||......::
  Rat   496 DETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDMMLAKHVITLHVSALTQTQAVEGEIDLAKM 559

  Fly   565 LRYVTFAR-QFKPVISQEAGHMLVENY----GHLRQRDTGTSGRSTWRITVRQLESMIRLSEAMA 624
            .:::.:.| :..|.:|.||...|...|    ...||.:.....||:..|||||||:::|::||::
  Rat   560 KKFIAYCRARCGPRLSAEAAEKLKNRYIIMRSGARQHERDIDRRSSIPITVRQLEAIVRIAEALS 624

  Fly   625 KLECSNRVLERHVKEAFRLLNKSII 649
            |::......|..|:||.||...|.:
  Rat   625 KMKLQPFATEADVEEALRLFQVSTL 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm6	NP_511065.1	MCM_N	25..109	CDD:379644	20/98 (20%)
		MCM	113..649	CDD:214631	185/551 (34%)
		MCM6_C	702..816	CDD:375690
Mcm5	XP_038953490.1	MCM_N	32..129	CDD:405270	22/101 (22%)
		MCM	133..649	CDD:214631	185/551 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820