Protein Alignment Mcm6 and Mcm7

DIOPT Version :9

• Sequence 1: NP_511065.1
• Gene: Mcm6 / 31603
• FlyBaseID: FBgn0025815
• Length: 817
• Species: Drosophila melanogaster
• Sequence 2: NP_001004203.3
• Gene: Mcm7 / 288532
• RGDID: 1303018
• Length: 719
• Species: Rattus norvegicus
• Alignment Length: 692
• Identity: 218/692 - (31%)
• Similarity: 337/692 - (48%)
• Gaps: 107/692 - (15%)

  Fly    11 LRVKDEVGIRAQKLFQDFLEEFKEDGEI-----KYTRPAASLESPDRCTLEVSFEDVEKYDQNLA 70
            :.:|| ..|..:|: :.||:||..|.|:     ||......|...::..|.|..:||.:.|..|.
  Rat     1 MALKD-YAIEKEKV-KKFLQEFYYDDELGKKQFKYGTQLVHLAHREQVALYVDLDDVAEDDPELV 63

  Fly    71 TAIIE---EYYHIYPFLCQS-VSNYVKDRIGLKTQKDCYV------------------------- 106
            .:|.|   .|..::..:.|. :..|.:..:..|...|.|:
  Rat    64 DSICENAKRYSRLFADVVQELLPEYKEKEVVNKDVLDVYIEHRLMMEQRSRDPGAVRNPQNQYPS 128

  Fly   107 -------AFTEVPTRHK---VRDLTTSKIGTLIRISGQVVRTHPVHPELVSGVFMCLDCQTEIRN 161
                   .:.:.|:..|   :|::....:|.|:.:.|.|.|...|.|.:|...:.|..|..|...
  Rat   129 ELMRRFELYFQGPSSSKPRVIREVRADSVGKLLTVRGIVTRVSEVKPRMVVATYTCDQCGAETYQ 193

  Fly   162 VEQQFKFTNPTICRNPVC-SNRK--RFMLDVEKSLFLDFQKIRIQETQAELPRGCIPRAVEIILR 223
            ..|...|....:|.:..| :||.  |..|....|.|:.||:::|||...::|.|.|||::.::|.
  Rat   194 PIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSKFIKFQEMKIQEHSDQVPVGNIPRSITVVLE 258

  Fly   224 SELVETVQAGDRYDFTGTLIVVPDVSVLAGVGTRAENSSRHKPGEGMDGVTGLK--ALGMRELNY 286
            .|.....|.||....||  |.:|   ||.                     ||.:  |.|:....|
  Rat   259 GENTRIAQPGDHVSVTG--IFLP---VLR---------------------TGFQQMAQGLLSETY 297

  Fly   287 RMAFLACSVQATTARFGGTDLPMSEVTAEDMKKQMTDAEWHKIYEMSKDRNLYQNLISSLFPSIY 351
            ..|.....:..:.....|.    .|::||::|:             ..:.:.|:.|.:|:.|.||
  Rat   298 LEAHRVVKMTKSEDDVSGA----GELSAEELKQ-------------IAEEDFYEKLAASIAPEIY 345

  Fly   352 GNDEVKRGILLQQFGGVAKTTTEKTSLRGDINVCIVGDPSTAKSQFLKQVSDFSPRAIYTSGKAS 416
            |:::||:.:||...|||.: :.:...:||:|::|::|||..||||.|..:...:||:.||:|:.|
  Rat   346 GHEDVKKALLLLLVGGVDQ-SPQGMKIRGNIHICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGS 409

  Fly   417 SAAGLTAAVVRDEESFDFVIEAGALMLADNGICCIDEFDKMDQRDQVAIHEAMEQQTISIARAGV 481
            |..||||||:||..|.:..:|.|||:|||.|:|||||||||.:.|:.||||.|||||||||:||:
  Rat   410 SGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGI 474

  Fly   482 RATLNARTSILAAANPINGRYDRSKSLQQNIQLSAPIMSRFDLFFILVDECNEVVDYAIARKIVD 546
            ..|||||.||||||||..|||:..:||:|||||.|.::|||||.:::.|..:...|..:|:.|..
  Rat   475 LTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITY 539

  Fly   547 LHSNIE------ESVERAYTREEVLRYVTFARQFKPVISQEAGHMLVENYGHLRQRDTGTSGRST 605
            :|.:..      |.::....|    ||:...|:.:|.:.......:...|..:| |:...|..:|
  Rat   540 VHQHSRQPPAQFEPLDMKLMR----RYIAMCRERQPTVPDSLADYITAAYVEMR-REARASKDAT 599

  Fly   606 WRITVRQLESMIRLSEAMAKLECSNRVLERHVKEAFRLLNKS 647
            : .:.|.|.:::|||.|:|:|...:.|.:..|.||.||:..|
  Rat   600 Y-TSARTLLAILRLSTALARLRMVDIVEKEDVNEAIRLMEMS 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mcm6	NP_511065.1	MCM_N	25..109	CDD:379644	23/124 (19%)
		MCM	113..649	CDD:214631	190/549 (35%)
		MCM6_C	702..816	CDD:375690
Mcm7	NP_001004203.3	MCM_N	12..165	CDD:291233	29/153 (19%)
		MCM	145..641	CDD:214631	190/546 (35%)
		P-loop_NTPase	376..515	CDD:304359	83/138 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D232729at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820