DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ctr1A and Ctr1C

DIOPT Version :9

Sequence 1:	NP_001245552.1	Gene:	Ctr1A / 31601	FlyBaseID:	FBgn0062413	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_651837.1	Gene:	Ctr1C / 43668	FlyBaseID:	FBgn0062411	Length:	270	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	103/294 - (35%)
Similarity:	138/294 - (46%)	Gaps:	77/294 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDHAHHSAPGVDHSMHHDHVGMHHDHSGIPAATASPMDAASMFDLIPDTSDLQASHA----GHAA 61
            ||  ||   |||.|..|.|   ||...|.|             :.:|.:|..:..|:    .|..
  Fly     1 MD--HH---GVDASEGHVH---HHASHGSP-------------EPVPPSSGHEGHHSPEMNHHGN 44

  Fly    62 HGAH-NHGGGSGTGMEHMMPMAFHFGYNETILFSWWHIETVAGLIGSMIAIFLLALMYEGLKYYR 125
            ||.| .||...|...:..|.|.||.|.:|||||.:|..|:...|..|.:.||::|::||.||::|
  Fly    45 HGEHTKHGHHEGGAHDMSMAMFFHTGDSETILFKFWRTESAMALTLSCLLIFMVAVLYEALKFFR 109

  Fly   126 EYLF-WK----------------------TYNLLEYRPVTGPQ----------RNPEAPRIPSPA 157
            |:|| |.                      .||...|.|.|..|          |:|..|.:..|.
  Fly   110 EWLFSWDRKRLAGGRDQYNRPRRYREANYNYNQPTYPPRTNQQSGTQVYAYRPRSPSMPPLQPPG 174

  Fly   158 AAAPSP------VQYVGEVVHKQ-PPS--------MLSINHLLQTLLHVLQVTLSFLLMLIFMTY 207
            .::|..      .|:....|.:. ||:        ..|..|:|||.||||||.:||||||:|||:
  Fly   175 RSSPQAQSSLILTQHTHHHVQENTPPAGRTTKLKVFCSGMHILQTFLHVLQVLISFLLMLVFMTF 239

  Fly   208 NVWLCLMVVLGAAVGYFLFCWKKSVIVDVTEHCH 241
            |||||:.|:|||.|||::||   :...:|.|||:
  Fly   240 NVWLCVAVLLGAGVGYYIFC---AFRTNVQEHCN 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ctr1A	NP_001245552.1	Ctr	79..226	CDD:282057	73/194 (38%)
Ctr1C	NP_651837.1	SelP_N	<23..56	CDD:282453	9/32 (28%)
Ctr1C	NP_651837.1	Ctr	63..258	CDD:282057	73/194 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435322
Domainoid	1	1.000	52	1.000	Domainoid score	I4266
eggNOG	1	0.900	-	-		E1_KOG3386
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	106	1.000	Inparanoid score	I3503
Isobase	1	0.950	-	0	Normalized mean entropy	S2329
OMA	1	1.010	-	-		QHG28914
OrthoDB	1	1.010	-	-		D130811at33392
OrthoFinder	1	1.000	-	-		FOG0000938
OrthoInspector	1	1.000	-	-		otm14791
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12483
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4018
SonicParanoid	1	1.000	-	-		X3487
	13	12.890