DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ctr1A and Slc31a1

DIOPT Version :9

Sequence 1:	NP_001245552.1	Gene:	Ctr1A / 31601	FlyBaseID:	FBgn0062413	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_780299.2	Gene:	Slc31a1 / 20529	MGIID:	1333843	Length:	196	Species:	Mus musculus

Alignment Length:	248	Identity:	96/248 - (38%)
Similarity:	125/248 - (50%)	Gaps:	59/248 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDHAHHSAPGVDHSMHHDHVGMHHDHSGIPAATASPMDAASMFDLIPDTSDLQASHAGHAAHGAH 65
            |:|.     |::|...|.|:||:|....|   |..|                   |.......:|
Mouse     1 MNHM-----GMNHMEMHHHMGMNHTDDNI---TMPP-------------------HHHPTTSASH 38

  Fly    66 NHGGGSGTGMEHMMPMAFHFGY-NETILFSWWHIETVAGLIGSMIAIFLLALMYEGLKYYREYLF 129
            :||||...   .||||.|:|.: |..:|||...|.|...:.|:.:|:||||:.|||||..||.|.
Mouse    39 SHGGGDSM---MMMPMTFYFDFKNVNLLFSGLVINTPGEMAGAFVAVFLLAMFYEGLKIAREGLL 100

  Fly   130 WKTYNLLEYR--PVTGPQRNPEAPRIPSPAAAAPSPVQYVGEVV---HKQ-PPSMLSINHLLQTL 188
            .|:...:.|.  ||.||.                      |.::   ||. ...|||..|||||:
Mouse   101 RKSQVSIRYNSMPVPGPN----------------------GTILMETHKTVGQQMLSFPHLLQTV 143

  Fly   189 LHVLQVTLSFLLMLIFMTYNVWLCLMVVLGAAVGYFLFCWKKSVIVDVTEHCH 241
            ||::||.:|:.|||||||||.:||:.|..||..|||||.|||:|:||:|||||
Mouse   144 LHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKAVVVDITEHCH 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ctr1A	NP_001245552.1	Ctr	79..226	CDD:282057	64/153 (42%)
Slc31a1	NP_780299.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..41		6/43 (14%)
Slc31a1	NP_780299.2	Ctr	51..181	CDD:367839	62/151 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6859
eggNOG	1	0.900	-	-		E1_KOG3386
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1399
Inparanoid	1	1.050	151	1.000	Inparanoid score	I4354
Isobase	1	0.950	-	0	Normalized mean entropy	S2329
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000938
OrthoInspector	1	1.000	-	-		oto92318
orthoMCL	1	0.900	-	-		OOG6_102787
Panther	1	1.100	-	-	LDO	PTHR12483
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4018
SonicParanoid	1	1.000	-	-		X3487
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.800