DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3224 and ZNF593

DIOPT Version :9

Sequence 1:	NP_572335.1	Gene:	CG3224 / 31600	FlyBaseID:	FBgn0029885	Length:	162	Species:	Drosophila melanogaster
Sequence 2:	NP_056955.2	Gene:	ZNF593 / 51042	HGNCID:	30943	Length:	134	Species:	Homo sapiens

Alignment Length:	142	Identity:	61/142 - (42%)
Similarity:	81/142 - (57%)	Gaps:	18/142 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SKRKKMHYGDTHLQRRWRVRNRRRDLDQIDDDLQ----TRSGELINQNVDLDKPGFAQFYCVHCA 65
            |:|...|...: |.|:.:.:.||.|||:|..:|:    .|.....|...|.|.||.....|:.||
Human     4 SRRTGAHRAHS-LARQMKAKRRRPDLDEIHRELRPQGSARPQPDPNAEFDPDLPGGGLHRCLACA 67

  Fly    66 KYFIDDTAMQAHFRTKVHKRRLKALEIEPYSIEEAERAAGRGSFVKPKKRAMETQPSKEDVVAGK 130
            :||||.|.::.|||:|.||:|||.|.:||||.||||||||.||:|.|::.|:.|:.|.|
Human    68 RYFIDSTNLKTHFRSKDHKKRLKQLSVEPYSQEEAERAAGMGSYVPPRRLAVPTEVSTE------ 126

  Fly   131 RIRVEVVPE-DT 141
                  ||| ||
Human   127 ------VPEMDT 132

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3224	NP_572335.1	UFD2	<49..119	CDD:227443	39/69 (57%)
ZNF593	NP_056955.2	UFD2	1..108	CDD:227443	47/104 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..57		16/53 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	82..134		32/63 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145093
Domainoid	1	1.000	51	1.000	Domainoid score	I11650
eggNOG	1	0.900	-	-		E1_COG5112
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41070
Inparanoid	1	1.050	101	1.000	Inparanoid score	I4997
Isobase	1	0.950	-	0	Normalized mean entropy	S1615
OMA	1	1.010	-	-		QHG54265
OrthoDB	1	1.010	-	-		D1445352at2759
OrthoFinder	1	1.000	-	-		FOG0003984
OrthoInspector	1	1.000	-	-		oto90811
orthoMCL	1	0.900	-	-		OOG6_103042
Panther	1	1.100	-	-	LDO	PTHR46095
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R155
SonicParanoid	1	1.000	-	-		X2745
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750