DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdc7 and AT4G16970

DIOPT Version :9

Sequence 1:	NP_727103.1	Gene:	Cdc7 / 31598	FlyBaseID:	FBgn0028360	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_193430.3	Gene:	AT4G16970 / 827405	AraportID:	AT4G16970	Length:	889	Species:	Arabidopsis thaliana

Alignment Length:	572	Identity:	134/572 - (23%)
Similarity:	237/572 - (41%)	Gaps:	114/572 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 TKQARNKSEEAINDLLTRIPDIGKLFDVHSRI---GNGTFSTVLLGTLRRESHLPDSLRRKFAIK 163
            |.:.:::.::|.::   .|||    ||.::.:   |:|.:..|...|.:.:.       .:||||
plant   380 TVRLKDQKDQAKHN---TIPD----FDSYTIVEEEGSGGYGIVYKATRKTDG-------TEFAIK 430

  Fly   164 HHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHDRFQDFYTRMDVPEIR 228
            .....:....:..|::.:.:.|||..::....|::...|...::..:.|||.......:||.:::
plant   431 CPHVGAQKYYVNNEIRMLERFGGKNCIIKHEGCLKNGDSDCIILEHLEHDRPDSLKREIDVYQLQ 495

  Fly   229 QYMRNLLVALRHVHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQHVNPPAARSSGSAAA--IA 291
            .|...:..||..:||..|:||||||.|||::|:..:..|:||.||..::....|:..|.||  :.
plant   496 WYGYCMFKALSSLHKQGVVHRDVKPGNFLFSRKTNKGYLIDFNLAMDLHQKYRRADKSKAASGLP 560

  Fly   292 AANNKNNNNNNNNNSKRPRERESKGDVQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDA 356
            .|:.|::....                   :|||          ::..:||...|   .:||:..
plant   561 TASKKHHTLVK-------------------SLDA----------VNRGTNKPSQK---TLAPNSI 593

  Fly   357 PEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQQQPQQQSQQQ----HPQRQPQLAQ 417
            .:.:  |....:..:.:.|:...|..:.......:..:..:..|..:.:::    | .|:..|..
plant   594 KKAA--GKTRARNDMTRWERLNSQGAEGSGLTSAKDVTSTRNNPSGEKRREPLPCH-GRKALLDF 655

  Fly   418 MDQTASTP-------SGSKYNTNRNVSAAAANNAKCVCFANP-SVCLN-------CLMKKEVHAS 467
            :.:|.|.|       |.:..:..:.|:|......|.:.:..| .:|.|       .:.||:...|
plant   656 LQETMSVPIPNHEVSSKAPTSMRKRVAALPGKAEKELLYLTPMPLCSNGRPEAGDVIEKKDGPCS 720

  Fly   468 RAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGDQAIR 532
              ||.|:|.|||..:...|...:|||:|||..|.::....||...|...|  .:|..:.|.:.:.
plant   721 --GTKGFRAPEVCFRSLHQGPKIDVWSAGVTLLYLIMGRTPFTGDPEQNI--KDIAQLRGSEELW 781

  Fly   533 KTALALDRMITLSQRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVDGSCEVCRNCDQYFFNCLC 597
            :.|...:|     :.|.|..|        |.|.:.....|:.:                     |
plant   782 EVAKLHNR-----ESSFPKEL--------YESRYLKGMELRKW---------------------C 812

  Fly   598 EDSDYLTEPLDAYECFPPSAYDLLDRLLEINPHKRITAEEALKHPFFTAAEE 649
            |.:....|.||.   .|.|..||:|:.|.:||.:||:||:||||.||....|
plant   813 ELNTKRREFLDV---IPLSLLDLVDKCLTVNPRRRISAEDALKHDFFHPVHE 861

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	126/542 (23%)
		PKc_like	<474..644	CDD:304357	47/169 (28%)
		PKc_like	<616..675	CDD:304357	18/34 (53%)
AT4G16970	NP_193430.3	PKc_like	401..856	CDD:304357	124/537 (23%)
AT4G16970	NP_193430.3	S_TKc	401..856	CDD:214567	124/537 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	72	1.000	Domainoid score	I3316
eggNOG	1	0.900	-	-		E1_KOG1167
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003769
OrthoInspector	1	1.000	-	-		otm3508
orthoMCL	1	0.900	-	-		OOG6_103228
Panther	1	1.100	-	-	O	PTHR11909
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2628
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.860