Protein Alignment Cdc7 and cdc7

DIOPT Version :10

• Sequence 1: NP_727103.1
• Gene: Cdc7 / 31598
• FlyBaseID: FBgn0028360
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_012816569.2
• Gene: cdc7 / 549335
• XenbaseID: XB-GENE-951314
• Length: 536
• Species: Xenopus tropicalis
• Alignment Length: 594
• Identity: 191/594 - (32%)
• Similarity: 274/594 - (46%)
• Gaps: 136/594 - (22%)

  Fly   113 INDLLTRIPDIGKLFDVHSRIGNGTFSTVLL--GTLRRESHLPDSLRRKFAIKHHIPTSHPDRIM 175
            |..|...:|.:..:|.:.|:||.||||:|.|  |.||....:      .||:||.||||||.||.
 Frog    13 IEKLYAAVPQLRNIFYIKSKIGEGTFSSVYLAIGRLRSGEDV------TFALKHLIPTSHPTRIA 71

  Fly   176 KELQCMTKMGGKENVVGIHCCMRYDASAAFVMPFMAHDRFQDFYTRMDVPEIRQYMRNLLVALRH 240
            .||||::..||::||:|:..|.|.......|||::.|:.|.|....:.:.|.::||.|||.|||.
 Frog    72 AELQCLSVAGGEDNVMGVKYCFRNKDHVVIVMPYLEHECFADILHSLSLEETKEYMFNLLKALRR 136

  Fly   241 VHKFDVIHRDVKPSNFLYNRRRREFLLVDFGLAQ----------HVNPPAARSSGSAAA----IA 291
            :|.|.::|||||||||||||..::|.||||||||          .|..|  :..||.:.    |.
 Frog   137 IHSFGIVHRDVKPSNFLYNRSLKKFALVDFGLAQGTPDTKIDLLKVLQP--KKQGSCSQNHPYII 199

  Fly   292 AANNKNNN-----NNNNNNSKRPRERE--------SKGDVQQIALDAGLGGAVKRMRLHEESN-- 341
            :.|..:.|     ..|:.:||:..:::        |.|:..|    .||.|:..:..:..|.|
 Frog   200 SGNWVHQNIPVLRKVNHVSSKQSVKKQWSHSGTHISTGNHGQ----EGLFGSSAQRSVFGERNFN 260

  Fly   342 --------KMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQQQQSQQQQ 398
                    ...||.|.       |.:.:|.:..
 Frog   261 VHSAVTTDNTTLKAVK-------PSKMLDVTTR-------------------------------- 286

  Fly   399 QPQQQSQQQHPQRQPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVCLNCLMKKE 463
                           :||.. :|.|..|.|. :.|:..|:....:..|.|:|...||..||.:..
 Frog   287 ---------------KLATR-KTVSAKSTSS-SVNKKASSICQTSLACDCYAKDQVCNICLARTR 334

  Fly   464 VHASRAGTPGYRPPEVLLKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPNDFIALAEIVTIFGD 528
            ..|.||||||:|.||||.|.|.||||:|:|:||:||||::|..|.||.|.:|..|||:|:||.|.
 Frog   335 QVAPRAGTPGFRAPEVLTKCPHQTTAIDMWSAGIIFLSLLSGRYHFFNAADDMNALAQIMTIRGS 399

  Fly   529 QAIRKTALALDRMITLSQRSRPLNLRKLCLRFRYRSVFSDAKLLKSYESVD-------GSCEVCR 586
            :...:.:....:.:..|:.....:|:.||...|      .|.||.:.:..|       ...::..
 Frog   400 KETIQASKCFGKNLLCSKELPSKDLKTLCEGLR------SAVLLPNGDQHDIQKQRAALQMQIME 458

  Fly   587 NCDQYF--------------FNCLC--EDSDYLTEPLDAYECFPPSAYDLLDRLLEINPHKRITA 635
            |.|.:|              .:|:.  ::.|......:.::..|..||.||||||::||..||||
 Frog   459 NQDGWFSPESSNITHASSMVASCVSAPDNMDIEQSNHNGWDRVPNEAYHLLDRLLDMNPATRITA 523

  Fly   636 EEALKHPFF 644
            ||||.||.|
 Frog   524 EEALIHPLF 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	187/580 (32%)
		Protein Kinases, catalytic domain	<474..644	CDD:473864	67/192 (35%)
		Protein Kinases, catalytic domain	<616..675	CDD:473864	21/29 (72%)
cdc7	XP_012816569.2	STKc_Cdc7	25..532	CDD:270921	187/580 (32%)
		Protein Kinases, catalytic domain	<318..>530	CDD:473864	78/217 (36%)