DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cdc7 and Asator

DIOPT Version :9

Sequence 1:	NP_727103.1	Gene:	Cdc7 / 31598	FlyBaseID:	FBgn0028360	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_651924.2	Gene:	Asator / 43794	FlyBaseID:	FBgn0039908	Length:	1349	Species:	Drosophila melanogaster

Alignment Length:	572	Identity:	109/572 - (19%)
Similarity:	189/572 - (33%)	Gaps:	207/572 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 LPATPRTTKQARN--------------KSEEAI----NDLLTRIPDIGKLFDVHSRIGNGTFSTV 141
            |||....:.|.||              |::|::    .|||.....:.:.:.|..:||.|.|..:
  Fly   123 LPAQDSYSHQPRNQVAVAAKDGILVDVKAKESVKMTSEDLLQPGHVVKERWKVVRKIGGGGFGEI 187

  Fly   142 LLGTLRRESHLPDSL-RRKFAIKHHIPTSHPDRIMK-ELQCMTKMGGKENVVGIHCCMRYDASAA 204
            ..|        .|.: |.:.|:|.. ....|.:::| |:..:.|:.|||:|.....|.|
  Fly   188 YEG--------QDLITREQVALKVE-SARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGR------ 237

  Fly   205 FVMPFMAHDRFQDFYTRMDVPEIRQYMR-----------------NLLVALRHVHKFDVIHRDVK 252
                   :|||.....::....:.:..|                 .:|.|:..:|....:|||:|
  Fly   238 -------NDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIK 295

  Fly   253 PSNFL-----YNRRRREFLLVDFGLAQHVN--------PPAA---RSSGSAAAIAAANNKNNNNN 301
            ||||.     ||.||  ..::|||||:...        |.||   |.:...|:|.|..|:....:
  Fly   296 PSNFSVGRLPYNCRR--VYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRH 358

  Fly   302 NN-----------NNSKRP----RERESKG-----------------DVQQI------------- 321
            ::           .|.:.|    :::|..|                 |::|.
  Fly   359 DDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRP 423

  Fly   322 --ALDAGLGGAVKRMRLHEESN---------------------KMPLKPVNDIAPSDAPEQSVDG 363
              |:..||.....:.|..:||:                     .:|:|  :|....:..:.:|..
  Fly   424 DYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISATGNPSIPIK--SDYMHGNITQMTVAA 486

  Fly   364 SNHVQPQLVQQEQQ-------QLQPQQQQQQQQQQQQSQQQQQPQQQSQQQHPQRQPQLAQMDQT 421
            ||....:.:::..:       ...|...:::..:...:....||.:.|.:  |..|...|..:|.
  Fly   487 SNASGTEYIRKRAEIETAHITATDPLNIKEKVDKNCNATSLAQPAKGSGE--PMVQHGNAANNQN 549

  Fly   422 ASTPSGSKYNTNRNVSAAAAN-------------------------------NAKCVCFANPSVC 455
            .::....:.:|..|...|.||                               |.:|   .|..:.
  Fly   550 ITSKGLQQQSTLTNSQVAIANIQSAPSMIEREDVQYTKLEEGAPTKFITMKPNGEC---DNVDIA 611

  Fly   456 LNCLM-KKEVHAS-----RAGTPG-----------YRPPEVLLKYPDQTTAV 490
            ..|:. :|.|.|:     ||...|           :..||:..|...:|..|
  Fly   612 AKCIFEQKHVEANDDIVGRASLSGVEQHYKSQIKKHNSPEIANKQIQRTGTV 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	98/524 (19%)
		PKc_like	<474..644	CDD:304357	5/17 (29%)
		PKc_like	<616..675	CDD:304357
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	61/284 (21%)
Asator	NP_651924.2	S_TKc	173..414	CDD:214567	58/264 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452737
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11909
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030