DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdc7 and CG12147

DIOPT Version :9

Sequence 1:	NP_727103.1	Gene:	Cdc7 / 31598	FlyBaseID:	FBgn0028360	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_649536.1	Gene:	CG12147 / 40651	FlyBaseID:	FBgn0037325	Length:	477	Species:	Drosophila melanogaster

Alignment Length:	386	Identity:	75/386 - (19%)
Similarity:	136/386 - (35%)	Gaps:	123/386 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 PATPRTTKQARNKSEEAINDLLTRIPDI---GKLFDVHSRIGNGTF------------------- 138
            |..|....:...:.:...::....:|:|   || :.:..|||||:|
  Fly    35 PPQPNHPHEKDQRQDRRFSEEKQSLPEIIVAGK-YRLLKRIGNGSFGELFQAEGLKYHEKVAIKL 98

  Fly   139 --STVLLGTLRRESHLPDSLRRKFAIKH--HIPTSHPDRIMKELQCMTKMGGK-ENVVGIHCCMR 198
              |||....|.||:.:...|:....|.|  |..|.....:|    .|..:|.. |:::.:  |.|
  Fly    99 ESSTVKHPLLPREARIYGILQGGLGIPHVKHYATEGAYNVM----VMDLLGPTLEDLLNL--CSR 157

  Fly   199 YDASAAFVMPFMAHDRFQDFYTRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFL--YNRR 261
               |.:.....|..|:                   :|..:..:|:...||||:||.|||  .||.
  Fly   158 ---SFSMKTTLMLADQ-------------------ILARVELLHRRCFIHRDIKPDNFLMGLNRH 200

  Fly   262 RREFLLVDFGLA---------QHVNPPAARSSGSAAAIAAANNKNNNNNNNNNSKRPRERESKGD 317
            :.:..::|||||         :|:.....|.....|..|:..            ....|:..:.|
  Fly   201 QTQVYMIDFGLAKKFYSLRTQKHIGYTENRDLVGTARYASVR------------AHYAEQSRRDD 253

  Fly   318 VQQIALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDA-------------PEQSVDGSNHVQP 369
            ::.:..          :.|:.:..::|.:.:.  |.|.|             |.|.:.....|:.
  Fly   254 LESVGY----------LLLYFQRGRLPWQGIR--AQSQAQKYEKIAEYKANIPLQQLCSGLPVEF 306

  Fly   370 QLVQQEQQQLQPQQQQQQQQQQQ------QSQ-------------QQQQPQQQSQQQHPQR 411
            .:..:..::|...::......||      ::|             :::.|:|||||:..:|
  Fly   307 FMYLKYCRKLHFAEKPDYVYLQQLFKVLFRNQYKVCDFLFDWVVLKRESPEQQSQQKGRER 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	70/354 (20%)
		PKc_like	<474..644	CDD:304357
		PKc_like	<616..675	CDD:304357
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	62/316 (20%)
CG12147	NP_649536.1	SPS1	67..>306	CDD:223589	59/291 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452721
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11909
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030