Protein Alignment Cdc7 and CkIalpha

DIOPT Version :10

• Sequence 1: NP_727103.1
• Gene: Cdc7 / 31598
• FlyBaseID: FBgn0028360
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Alignment Length: 335
• Identity: 72/335 - (21%)
• Similarity: 122/335 - (36%)
• Gaps: 49/335 - (14%)

  Fly   123 IGKLFDVHSRIGNGTFSTVLLGTLRRESHLPDSLRRKFAIK-HHIPTSHPDRIMKELQCMTKMGG 186
            :|..:.|..:||:|:|..:.||...:..       .:.||| ......||..:.:........||
  Fly    16 VGGKYRVIRKIGSGSFGDIYLGMSIQSG-------EEVAIKMESAHARHPQLLYEAKLYRILSGG 73

  Fly   187 KENVVGIHCCMRYDASAAF---VMPFMA---HDRFQDFYTR-MDVPEIRQYMRNLLVALRHVHKF 244
                ||......:.....|   ||..:.   .|.| :|.|| ..:..:...:..::..|.::|..
  Fly    74 ----VGFPRIRHHGKEKNFNTLVMDLLGPSLEDLF-NFCTRHFTIKTVLMLVDQMIGRLEYIHLK 133

  Fly   245 DVIHRDVKPSNFL--YNRRRREFLLVDFGLAQHVNPPAARSSGSAAAIAAANNKN---------- 297
            ..||||:||.|||  ..|...:..|:|||||:....|..|..     |....:||
  Fly   134 CFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHH-----IVYREDKNLTGTARYASI 193

  Fly   298 NNNNNNNNSKRPRERESKGDVQQ-----IALDAGLGGAVKRMRLHEESNKMPLKPVNDIAPSDAP 357
            |.:.....|:|. :.||.|.|..     :....|:....|:.:..:.|.|....|:..:......
  Fly   194 NAHLGIEQSRRD-DMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPA 257

  Fly   358 EQSVDGSNHVQPQLVQQEQQQLQPQQQ-----QQQQQQQQQSQQQQQPQQQSQQQHPQRQPQLAQ 417
            |.|: ..|:.:....:::...:..:|.     :....|..........:|::.|..|.....|.|
  Fly   258 EFSM-YLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTHQGQPNPAILLEQ 321

  Fly   418 MDQTASTPSG 427
            :|:.....:|
  Fly   322 LDKDKEKQNG 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	71/333 (21%)
		Protein Kinases, catalytic domain	<474..644	CDD:473864
		Protein Kinases, catalytic domain	<616..675	CDD:473864
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	63/283 (22%)