DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cdc7 and CG2577

DIOPT Version :9

Sequence 1:	NP_727103.1	Gene:	Cdc7 / 31598	FlyBaseID:	FBgn0028360	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_572794.1	Gene:	CG2577 / 32188	FlyBaseID:	FBgn0030384	Length:	344	Species:	Drosophila melanogaster

Alignment Length:	189	Identity:	47/189 - (24%)
Similarity:	76/189 - (40%)	Gaps:	36/189 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 FDVHSRIGNGTFSTVLLGTLRRESHLPDSLRRKFAIK------HHIPTSHPDRIMKELQCMTKMG 185
            :.|..:||.|:|..:.||......       .:.|||      .|...::..||.:.|:   ...
  Fly    17 YKVVRKIGCGSFGDIYLGIYIHSG-------ERVAIKVESSKVRHPQLNYERRIYRALR---PAH 71

  Fly   186 GKENVVGIHCCMRYDASAAFVMPFM--AHDRFQDFYTR-MDVPEIRQYMRNLLVALRHVHKFDVI 247
            |...:...|....|.   |.||..:  :.:|...|..| ..:..:......:|..:.:||....:
  Fly    72 GLPRIRYFHKEEHYQ---AMVMDLLGPSLERLFQFCERAFTIKTVLLLAEQMLRRVEYVHNRGFL 133

  Fly   248 HRDVKPSNFL--YNRRRREFLLVDFGLAQ---------HVNPPAARS-SGSA--AAIAA 292
            |||:||.|||  .....::..|:||||::         |:.....|| :|:|  |:|.|
  Fly   134 HRDIKPDNFLMGLGTMSKQVYLIDFGLSKKYLDITTGVHIPYREERSLTGTARYASIGA 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	47/189 (25%)
		PKc_like	<474..644	CDD:304357
		PKc_like	<616..675	CDD:304357
CG2577	NP_572794.1	STKc_CK1	16..281	CDD:270918	47/189 (25%)
CG2577	NP_572794.1	SPS1	16..>242	CDD:223589	47/189 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452723
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11909
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030