Protein Alignment Cdc7 and cdc-7

DIOPT Version :9

• Sequence 1: NP_727103.1
• Gene: Cdc7 / 31598
• FlyBaseID: FBgn0028360
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_491705.1
• Gene: cdc-7 / 172260
• WormBaseID: WBGene00016421
• Length: 411
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 115/530 - (21%)
• Similarity: 184/530 - (34%)
• Gaps: 198/530 - (37%)

  Fly   133 IGNGTFSTVLLGTLRRESHLPDSLRRKFAIKHHIPTSHPDRIMKELQCMTKMGGKENVVGIHCCM 197
            ||.|:|.||:..|.|       :.:.|.|||..........:..||:.::::||..|:|.:....
 Worm    34 IGEGSFGTVISATCR-------TTQEKRAIKAIRRIEKMSMLSIELELLSELGGHFNIVKLFEFF 91

  Fly   198 RYDASAAFVMPFMAHDRFQD--FYTRMDVPEIRQYMRNLLVALRHVHKFDVIHRDVKPSNFLYNR 260
            .::.|.|.|:....|....:  |:::.|:.....|.||||.|:.::|....:|||:|.|||||:.
 Worm    92 HFNGSVAIVLEHFPHCTATELLFHSKRDLSFALSYFRNLLYAVAYLHHNGYVHRDIKLSNFLYSP 156

  Fly   261 RRREFLLVDFGLAQHVNPPAARSSGSAAAIAAANNKNNNNNNNNNSKRPRERESKGDVQQIALDA 325
            :.:.|.|||||||                 ....:||..:.::
 Worm   157 QTQRFRLVDFGLA-----------------TVDRSKNECSRSH---------------------- 182

  Fly   326 GLGGAVKRMRLHEESNKMPLKPVNDIAPSDAPEQSVDGSNHVQPQLVQQEQQQLQPQQQQQQQQQ 390
                ||..|
 Worm   183 ----AVAAM-------------------------------------------------------- 187

  Fly   391 QQQSQQQQQPQQQSQQQHPQRQPQLAQMDQTASTPSGSKYNTNRNVSAAAANNAKCVCFANPSVC 455
                               :|.|:.                              |.|....|.|
 Worm   188 -------------------ERDPEC------------------------------CSCKGTSSPC 203

  Fly   456 LNCLMK-KEVHASRAGTPGYRPPEVL----LKYPDQTTAVDVWAAGVIFLSIMSTVYPFFKAPND 515
            :.|..| |..:.:..||||.|.||:|    |.:|    ::|:::.|::.||::|..:|||...::
 Worm   204 MFCRGKPKRENYNVVGTPGVRAPELLFGIGLCHP----SIDIFSCGIVLLSLVSVKHPFFMPKDE 264

  Fly   516 FIALAEIVTIFGDQAIRKTALALDRMITLSQRSRPLNLRK--LCLRFRYRSVFSDAKLLKSYESV 578
            ...:..:..:.|.:.|.|.|.:....:|||::..|.:...  |||||.:..|         ....
 Worm   265 TENIMHLAFLLGSETIEKMAHSEGLRVTLSEKLPPADYYHLILCLRFGFDHV---------RRHC 320

  Fly   579 DGSCEVCRNCDQYFFN-----CLCE---DSDYL------TEPLDAYECFPPSAYDLLDRLLEINP 629
            ..|.:.|..|.:..||     |.|.   ::|..      ||.:..|       .|||.|.||.:.
 Worm   321 SSSRQPCTICQKRSFNNSMGVCFCRKNYETDMFSTGGNETELMTIY-------VDLLYRTLEADR 378

  Fly   630 HKRITAEEAL 639
            .||..|::.|
 Worm   379 FKRYNADQLL 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc7	NP_727103.1	STKc_Cdc7	125..644	CDD:270921	115/530 (22%)
		PKc_like	<474..644	CDD:304357	49/186 (26%)
		PKc_like	<616..675	CDD:304357	10/24 (42%)
cdc-7	NP_491705.1	PKc_like	34..277	CDD:389743	80/401 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166305
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1167
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	132	1.000	Inparanoid score	I3181
Isobase	1	0.950	-	0	Normalized mean entropy	S4005
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1361975at2759
OrthoFinder	1	1.000	-	-		FOG0003769
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103228
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2628
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.700