Protein Alignment CG3226 and Cacybp

DIOPT Version :10

• Sequence 1: NP_572332.1
• Gene: CG3226 / 31597
• FlyBaseID: FBgn0029882
• Length: 230
• Species: Drosophila melanogaster
• Sequence 2: NP_033916.1
• Gene: Cacybp / 12301
• MGIID: 1270839
• Length: 229
• Species: Mus musculus
• Alignment Length: 224
• Identity: 88/224 - (39%)
• Similarity: 133/224 - (59%)
• Gaps: 20/224 - (8%)

  Fly     3 LEQLKSDVAELAAFLQQAKGARVKDVLTTAKAEAEREIVN-----LELKAKIAAERQA------- 55
            ||:|:.|:.|:...|:::...|::|.||:.|::.|.|:.|     .:.|.::..|:.|
Mouse     5 LEELQKDLEEVKVLLEKSTRKRLRDTLTSEKSKIETELKNKMQQKSQKKPELDNEKPAAVVAPLT 69

  Fly    56 TGSSEAKRYLHELTDYGWDQSAKFVKLFITLNGVQGCTEENVTVTYTPNSLQLHVRDLQGKDFGL 120
            ||      |..::::||||||.||||::|||.||.....|||.|.:|..|..|.|::|.||::.:
Mouse    70 TG------YTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKNYSM 128

  Fly   121 TVNNLLHSIDVEKSYRKIKTDMVAIYL-QKVEDKHWDVLTAIQKRLKQKKDSELSKDGDNPESAL 184
            .|||||..|.||.|.:|:|||.|.|.. :|.|:..||.||.::|..|:|:......:.| |...|
Mouse   129 IVNNLLKPISVESSSKKVKTDTVIILCRKKAENTRWDYLTQVEKECKEKEKPSYDTEAD-PSEGL 192

  Fly   185 VNIMKKMYNDGDSKTKQMIAKAWTESQDK 213
            :|::||:|.|||...|:.|.|||.||::|
Mouse   193 MNVLKKIYEDGDDDMKRTINKAWVESREK 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3226	NP_572332.1	Siah-Interact_N	1..>60	CDD:462660	19/68 (28%)
		p23_CacyBP	68..159	CDD:107225	45/91 (49%)
Cacybp	NP_033916.1	Interaction with SIAH1. /evidence=ECO:0000250	2..81		21/81 (26%)
		Siah-Interact_N	3..76	CDD:462660	20/76 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..60		4/21 (19%)
		Interaction with SKP1. /evidence=ECO:0000250	74..229		68/149 (46%)
		p23_CacyBP	76..168	CDD:107225	45/91 (49%)
		Interaction with S100A6	155..229		27/68 (40%)
		SGS	183..>218	CDD:461514	15/35 (43%)