DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pigs and macf1a

DIOPT Version :9

Sequence 1:	NP_001245550.1	Gene:	pigs / 31596	FlyBaseID:	FBgn0029881	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	XP_017207777.1	Gene:	macf1a / 562190	ZFINID:	ZDB-GENE-030131-3606	Length:	8259	Species:	Danio rerio

Alignment Length:	394	Identity:	98/394 - (24%)
Similarity:	153/394 - (38%)	Gaps:	108/394 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 TNDLKSLDEMVRDLVEKCTCPSQFPMVRVSEGKYR------IGDTKVLIFVRILRSHVMVRVGGG 309
            |.|...:::.|...|.:|.|..:|.:.::.|.|||      .||::.|..||||||.||||||||
Zfish  7925 TTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGG 7989

  Fly   310 WDTLSHYLDKHDPCR--------CRAQHRSSVAARLIPRQSPNH-----NPSNGIELHKAQVIFE 361
            |..|..:|.|:||||        .|:...||:::|:: ..:|.:     .....:||.:..::.|
Zfish  7990 WMALDEFLVKNDPCRVQHPGLKILRSDSSSSISSRIV-TVTPGYFCCRARGRTNLELREKFILPE 8053

  Fly   362 --------------RSPPAARRVFNSPNCNGGPGTGSSCGTGVVGVAVPPTLQNGHSLSPNSGKY 412
                          ||.|::|....:.:.:....:..||.: |......||..:..|.|.:.|..
Zfish  8054 GATQGLAAFRSRGRRSKPSSRTASPTRSSSSASHSAHSCAS-VPSAPATPTASSRSSQSQSRGYA 8117

  Fly   413 R-----SRSPTPQR-----KFLNQQANGGGIASATGSSQTVTTDTSSGQLL----GSPSLARRSM 463
            :     |::|||.:     :......:.||   :|...:..|..:|.|.|.    |:|:.|:...
Zfish  8118 KPWLAHSKTPTPTKCQSCPEHSQTPGHEGG---STTKLKRPTFHSSRGSLTGENGGTPTAAKPGR 8179

  Fly   464 SPSPRRLIDMRKKQSSLDSYSSGPKSLPGYSCSMEEANGGSGVGSAAGGVSSGSAGSGVAGEQGG 528
            |.:.|           ..|.:|||.|           ..||..||.|.
Zfish  8180 SETKR-----------TPSSTSGPAS-----------RAGSRAGSRAS----------------- 8205

  Fly   529 ANKFENISDNGSEISDEGYRSLGVIQSGAQKRESLHSQASIEDAESNARLDQTSSDSQISPSDE- 592
                   |..||:.||         .|...:..|..|..|.......|:..:..:.|:.:||.:
Zfish  8206 -------SRRGSDASD---------TSELMETRSACSDTSDTPRRPGAKPSKIPTISKKTPSPKT 8254

  Fly   593 PAEK 596
            ||.|
Zfish  8255 PAGK 8258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pigs	NP_001245550.1	CH	22..159	CDD:237981
pigs	NP_001245550.1	GAS2	258..325	CDD:280367	34/80 (43%)
macf1a	XP_017207777.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810