DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pigs and asp

DIOPT Version :9

Sequence 1:	NP_001245550.1	Gene:	pigs / 31596	FlyBaseID:	FBgn0029881	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	NP_524488.3	Gene:	asp / 42946	FlyBaseID:	FBgn0000140	Length:	1954	Species:	Drosophila melanogaster

Alignment Length:	559	Identity:	114/559 - (20%)
Similarity:	175/559 - (31%)	Gaps:	194/559 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   587 ISPSDEPAE-KATTDILEEEDLNGQDRE-----EDQEDYSVCDGPQSLPAILSGAHKLSDKFEQS 645
            ::|||:..| |....|.||.:|:.:..|     .|:....:...|     :|..|.|.:.:...:
  Fly    56 LNPSDDDIEVKVMKAIREEHNLSLEWMEHTVPARDEVSMELVWSP-----VLEVACKETLQLIDN 115

  Fly   646 GVFITDDEITVDIAKTEDQSVANTMGNPTPNLSKIPRSPL-AQRRRRSIDNSTCGGAGGSLQDLS 709
            ..|  ..|:.:.:....:|.|.|....||...:...:||. |.:..:|:       ...::|...
  Fly   116 RNF--RKEVMIILKSKSNQPVKNPRKFPTVGKTLQLKSPTGAGKTMKSV-------VSAAVQQKK 171

  Fly   710 SRSGLPAPAFSRKQPVYRSVRTRNSTGATTTPVAP---------PRSRQATQLPMVRDVTNTWSG 765
            ..|...||  ..||....:..:|.:..|...|.||         |:.......|..|.:....|.
  Fly   172 RMSAAAAP--PSKQTWRVTAPSRPAAWAHPPPQAPLVEKNVYKTPQEEPVYISPQPRSLKENLSP 234

  Fly   766 RTTG------APKRRPPCTADTFVAPTNGTGPAGSFERN--------GKGRSSQILYDSNGRRVR 816
            .|.|      ...|..|.|      .|.|.|.|..|..|        .||.......|...||:.
  Fly   235 MTPGNLLDVIDNLRFTPLT------ETRGKGQATIFPDNLAAWPTPTLKGNVKSCANDMRPRRIT 293

  Fly   817 ----------------------------------SGAPGCTSSLTTSPVKNHAS----------- 836
                                              .|.|....:.||:.|  ||:
  Fly   294 PDDLEDQPATNKTFDVKHSETINISLDTLDCSRIDGQPHTPLNKTTTIV--HATHTRALACIHEE 356

  Fly   837 ---SPLAQQLLEAASSAKNDAQIL--------EKMK--SLLS---RYAAG------NQTK----- 874
               ||.......|....|.|.:::        |.||  ||||   :||..      |:.|
  Fly   357 EGPSPPRTPTKSAIHDLKRDIKLVGSPLRKYSESMKDLSLLSPQTKYAIQGSMPNLNEMKIRSIE 421

  Fly   875 ---------------------------AG----------------------VGATATAANKINSN 890
                                       ||                      ||..:...:.:.:.
  Fly   422 QNRYYQEQQIQIKAKDLNSSSSSEASLAGQQEFLFNHSEILAQSSRFNLHEVGRKSVKGSPVKNP 486

  Fly   891 GKKTPVYEDFTTAWVHSNGNLERSE--SCSPPAKARSK-----RSSAASSCESNNSNAGAGSGA- 947
            .|:......|:.|  .||.:|.|:|  :.|||.|.|.:     ||:|.::..:.:|:|.|...|
  Fly   487 HKRRSHELSFSDA--PSNESLYRNETVAISPPKKQRVEDTTLPRSAAPANASARSSSAHAWPHAQ 549

  Fly   948 -----AAGSASVV----SPRRERGMSKIPAPVRHHTELY 977
                 .|.:.|::    :||:.|..|..|:...:.:|||
  Fly   550 SKKFKLAQTMSLMKKPATPRKVRDTSIQPSVKLYDSELY 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pigs	NP_001245550.1	CH	22..159	CDD:237981
pigs	NP_001245550.1	GAS2	258..325	CDD:280367
asp	NP_524488.3	ASH	26..122	CDD:292408	16/72 (22%)
		CH	866..968	CDD:237981
		TPH	1066..1435	CDD:290579
		IQ	1689..1711	CDD:197470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452297
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930