Protein Alignment pigs and Dst

DIOPT Version :10

• Sequence 1: NP_572331.2
• Gene: pigs / 31596
• FlyBaseID: FBgn0029881
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: XP_017452259.1
• Gene: Dst / 316313
• RGDID: 1306566
• Length: 7735
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 134/614 - (21%)
• Similarity: 211/614 - (34%)
• Gaps: 193/614 - (31%)

  Fly    20 EAMREDLAEWL----STLYPELSINADNFMDRLDTGVALCKHANYV-----RQAAVDYLARRQAR 75
            :.:.|:|..||    :||..:........::.:.|.:|  :|..::     :|..||.:.:...|
  Rat  7164 QELLENLLAWLQWAETTLTEKDKEVIPQEIEEVKTLIA--EHQTFMEEMTRKQPDVDKVTKTYKR 7226

  Fly    76 NKSMTRSMTSGLAGPILAMGNV--------HYLPAAKSGTFFARDNVSNFIT--WCRKSLKIIEC 130
            ..:...|:.|.:  |:|..|..        ...|:........::..:|.:.  |.:..|..:|
  Rat  7227 RAADPPSLQSHI--PVLDKGRAGRKRFPASGLYPSGSQTQIETKNPRANLLVSKWQQVWLLALE- 7288

  Fly   131 LLFETDDLIMRKNEKHVILCLLEVARRGAKFGM-------------LAPMLVQMERQIDREIAAD 182
                      |:.:.:..|..||..|..|.|..             ....::...|:||::....
  Rat  7289 ----------RRRKLNDALDRLEELREFANFDFDIWRKKYMRWMNHKKSRVMDFFRRIDKDQDGK 7343

  Fly   183 IKANGAGCSENGTQTDALETGNSSAATMTTITTTTVETDLYDDSDD---------SETEDDGDQN 238
            |           |:.:.:: |..|:...|:....:...|::|...|         :....:.|
  Rat  7344 I-----------TRQEFID-GILSSKFPTSRLEMSAVADIFDRDGDGYIDYYEFVAALHPNKD-- 7394

  Fly   239 PVLMYGPQPQIITNDLKSLDEMVRDLVEKCTCPSQFPMVRVSEGKYR------IGDTKVLIFVRI 297
               .|.|    ||:..|..||:.|. |.||.|..:|.:.::.:.|||      .||::.|..|||
  Rat  7395 ---AYKP----ITDADKIEDEVTRQ-VAKCKCAKRFQVEQIGDNKYRFFLGNQFGDSQQLRLVRI 7451

  Fly   298 LRSHVMVRVGGGWDTLSHYLDKHDPCR--------CRAQHRSSVAA----------------RLI 338
            |||.|||||||||..|..:|.|:||||        .|::..||:.|                :.|
  Rat  7452 LRSTVMVRVGGGWMALDEFLVKNDPCRVHHHGSKMLRSESNSSITATQPTLAKGRTNMELREKFI 7516

  Fly   339 -------------PR----------QSPNHNPSNGIELHKAQVIFERSPPAA---------RRVF 371
                         ||          .|||.  |.....|..|....:.|.||         .|.:
  Rat  7517 LADGASQGMAAFRPRGRRSRPSSRGASPNR--STSASSHACQAASPQVPAAASTPKILHPLTRNY 7579

  Fly   372 NSP--------------NCNGGPGTGSSCGTGVVG--VAVPPTL--QNGHSLSPNS--------- 409
            ..|              .|...| ..|:.||.:.|  :.:|..|  :..||...|:
  Rat  7580 GKPWLANSKMSTPCKAAECPDFP-VSSAEGTPIQGSKLRLPGYLSGKGFHSGEDNALITTAASRV 7643

  Fly   410 -GKYRSRSPTPQRKFLNQQANGGGIASATGSSQTVTTDTSSGQLLGS------------------ 455
             .::.....||.|......:..|..||:...|.....|.|..|.:.|
  Rat  7644 RTQFAESRKTPSRPGSRAGSKAGSRASSRRGSDASDFDISEIQSVCSDVETVPQTHRPAPRAGSR 7708

  Fly   456 PSLARRSMSPSPRRLIDMRKKQSSLDSYS 484
            ||.|:.|..|:|:|    :...|.||..|
  Rat  7709 PSTAKPSKIPTPQR----KSPASKLDKSS 7733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pigs	NP_572331.2	CH_GAS2L1_2	11..163	CDD:409117	30/161 (19%)
		GAS2	257..325	CDD:460480	36/81 (44%)
Dst	XP_017452259.1	CH_SF	201..358	CDD:469584
		CH_DYST_rpt2	363..466	CDD:409088
		SPEC	819..910	CDD:197544
		SPEC	912..1101	CDD:238103
		SH3_10	1087..1153	CDD:407754
		Spectrin_like	1188..1265	CDD:465730
		CCDC158	<1318..>1756	CDD:464943
		Plectin	1798..1836	CDD:459901
		Plectin	1987..2025	CDD:459901
		SMC_prok_B	3743..4547	CDD:274008
		SPEC	4046..4280	CDD:238103
		SPEC	4641..4862	CDD:238103
		SPEC	4867..5081	CDD:238103
		SPEC	5083..5294	CDD:238103
		SPEC	5226..5402	CDD:413338
		SPEC	5409..5624	CDD:238103
		SPEC	5523..5736	CDD:238103
		SPEC	5630..5845	CDD:238103
		SPEC	5748..5954	CDD:238103
		SPEC	5958..6171	CDD:238103
		SPEC	6068..6284	CDD:238103
		SPEC	6286..6503	CDD:238103
		SPEC	6398..6612	CDD:238103
		SPEC	6506..6721	CDD:238103
		SPEC	6614..6830	CDD:238103
		SPEC	6832..7048	CDD:238103
		SPEC	6945..7157	CDD:238103
		SPEC	7167..7294	CDD:197544	24/141 (17%)
		EFh	7328..7390	CDD:238008	11/73 (15%)
		GAS2	7403..7478	CDD:128539	35/75 (47%)
		PHA03307	7542..>7735	CDD:223039	44/199 (22%)