DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment pigs and Dsp

DIOPT Version :9

Sequence 1:NP_001245550.1 Gene:pigs / 31596 FlyBaseID:FBgn0029881 Length:977 Species:Drosophila melanogaster
Sequence 2:XP_225259.4 Gene:Dsp / 306871 RGDID:1305794 Length:2877 Species:Rattus norvegicus


Alignment Length:447 Identity:94/447 - (21%)
Similarity:149/447 - (33%) Gaps:153/447 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   433 IASATGSSQTVTTDTSSGQLLGSPSLARRSMSPSPRRLIDMRKKQSSLDSYSSGPKSLPGYSCSM 497
            |..:.||::.|..|..:|..........:.       |:|    :...|.|.||..||..::..:
  Rat  2515 ITGSDGSTRVVLVDRKTGSQYDIQDAIDKG-------LVD----RKFFDQYRSGSLSLTQFADMI 2568

  Fly   498 EEANGGSGVGSAAGGVSSGSAGSGV--AGEQGGANKFENISD------NGSEISD---------- 544
            ...|   |||:::|  .|||....|  :......:|...||.      ..|.:||          
  Rat  2569 SLKN---GVGTSSG--LSGSVNDDVFSSSRHESVSKISTISSVRNLTIRSSSLSDPLEESSPIAA 2628

  Fly   545 -------------EGYRSLGVIQSGAQKRESLHSQA--------------SIEDAESNARLDQTS 582
                         ||... |::.|...:| .|.:||              |::||.|...:||  
  Rat  2629 IFDTENLEKISITEGIER-GIVDSITGQR-LLEAQACTGGIIHPTTGQKLSLQDAVSQGLIDQ-- 2689

  Fly   583 SDSQISPSDEPAEKATTDILEEEDLNGQDR----EEDQEDYSVCDGPQSLPAILSGAHKLSDKFE 643
               .::...:||:||   .:..|.:.|:.:    |..:|.:        || ..:|...|..:|.
  Rat  2690 ---DMATRLKPAQKA---FIGFEGVKGKKKMSAAEAVKEKW--------LP-YEAGQRFLEFQFL 2739

  Fly   644 QSGVFITDDEITVDIAKTEDQSVANTMGNPTPNLSKIPRSPLAQRRRRSIDNSTCGGAGGSLQDL 708
            ..|  :.|.|:...|: ||:..                       |:..||    |.|...|||:
  Rat  2740 TGG--LVDPEVHGRIS-TEEAI-----------------------RKGFID----GRAAQRLQDI 2774

  Fly   709 SSRSGLPAPAFSRKQPVYRSVRTRNSTGATTTPVAPPRSRQATQLPMVRDVT-----NTWSGRTT 768
            ||.:.:.....::.:..|:....|:                     ||.|:|     ...|..:.
  Rat  2775 SSYAKILTCPKTKLKISYKDAMNRS---------------------MVEDITGLRLLEAASVSSK 2818

  Fly   769 GAPKRRPPCTADTFVAPTNGTGPAG-SFERNGKGRSSQILYDSNGRRVRSGAPGCTS 824
            |.|            :|.|.:.|.. |..|:|....|:....|..||....|.|.:|
  Rat  2819 GLP------------SPYNMSAPGSRSGSRSGSRSGSRSGSRSGSRRGSFDATGNSS 2863

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pigsNP_001245550.1 CH 22..159 CDD:237981
GAS2 258..325 CDD:280367
DspXP_225259.4 SPEC 197..373 CDD:295325
SPEC 292..457 CDD:238103
Cast 1032..1681 CDD:287183
DUF2570 <1276..>1349 CDD:305162
GBP_C <1318..1412 CDD:303769
coiled coil 1382..1393 CDD:293879
coiled coil 1402..1412 CDD:293879
End3 <1514..1662 CDD:289527
Taxilin 1524..1839 CDD:286771
Plectin 2055..2093 CDD:279071
PLEC 2091..2128 CDD:197605
Plectin 2130..2171 CDD:279071
Plectin 2260..2300 CDD:279071
Plectin 2298..2338 CDD:279071
PLEC 2335..2371 CDD:197605
Plectin 2373..2414 CDD:279071
Plectin <2475..2505 CDD:279071
PLEC 2618..2654 CDD:197605 5/36 (14%)
Plectin 2656..2695 CDD:279071 10/44 (23%)
Plectin 2732..2773 CDD:279071 14/70 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0516
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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