DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pigs and BC024139

DIOPT Version :9

Sequence 1:	NP_001245550.1	Gene:	pigs / 31596	FlyBaseID:	FBgn0029881	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	NP_001136440.1	Gene:	BC024139 / 271278	MGIID:	2442591	Length:	772	Species:	Mus musculus

Alignment Length:	390	Identity:	80/390 - (20%)
Similarity:	132/390 - (33%)	Gaps:	88/390 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AMLEARPYRPFKSSEEYLEAMREDL---AEWLSTLYPELSINADNFMDRL----DTGVALCKHAN 59
            |||:| ..:|.:.  .:||...:|.   |.|...:.....:.....:::|    |...:|.:...
Mouse   360 AMLQA-DTKPLEG--HWLETREQDFGPKAIWEPAVQISCGLADQAAIEKLKPERDWNPSLQEFLW 421

  Fly    60 YVRQAAVDYLARRQARNKSMT--RSMTSGLAGPILAMGN-----VHYLPAAKSGTFFARDNVSNF 117
            ..:..||.:|.||.|.:...|  ..:...|.|...||.:     :|.|    .|....   |.:.
Mouse   422 EQQTLAVSWLGRRGAADYGSTCHLGLLMDLQGCRAAMSSPSCERIHTL----EGVLLL---VGHL 479

  Fly   118 ITWCRKSLKIIEC--LLFETDDLIMRKNEKHVILCLLEVARRGAKFGMLAPMLVQMERQIDREIA 180
            :.      |::.|  .|.:.:.|.::..:.|.:|..:..|.. .|:...||..:.....:|:|..
Mouse   480 VE------KLVLCPHRLSQAEPLGIKVVQAHSLLEEMPPALT-PKYWTRAPREILALMSLDQEPP 537

  Fly   181 ADIKANGAGC---------SENGTQTDALETGNSSAATMTTITTTTVETDLYDDSDDSETEDDGD 236
            .|:.:....|         |.....::.:|..:                 |........:||..|
Mouse   538 GDLASRAKACLLGKIPKELSWRPWWSEVMENWS-----------------LRKPEHSKRSEDKRD 585

  Fly   237 QNPVLMYGPQPQIITNDLKSLDEM-------------VRDLVEKCTC------------PSQFPM 276
            |...|..|.|.|...:...|.:|.             .|..:.|.:.            |:....
Mouse   586 QWERLEQGHQVQDPADSFLSTEEQDSVGQGWPSYNWGRRGPLHKVSITFKPGLSSGQKQPNSVVR 650

  Fly   277 VRVSEGKYRI---GDTKVLIFVRILRSHVMVRVGGGWDTLSHYLDKHDPCRCRAQHRSSVAARLI 338
            .|..||....   |..||. .....|..:||||||||..|..:|.|:||.|.:.:....:..|.:
Mouse   651 ARNPEGSSASGARGRPKVQ-GALAARGAMMVRVGGGWAALDEFLVKNDPVRAKGRTSQKIHERFL 714

Fly 339 338
Mouse 715 714

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pigs	NP_001245550.1	CH	22..159	CDD:237981	28/152 (18%)
pigs	NP_001245550.1	GAS2	258..325	CDD:280367	24/94 (26%)
BC024139	NP_001136440.1	SPEC	<157..267	CDD:295325
BC024139	NP_001136440.1	GAS2	<675..701	CDD:295345	14/25 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900