DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pigs and csp-2

DIOPT Version :9

Sequence 1:	NP_001245550.1	Gene:	pigs / 31596	FlyBaseID:	FBgn0029881	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	NP_001370851.1	Gene:	csp-2 / 177391	WormBaseID:	WBGene00000820	Length:	826	Species:	Caenorhabditis elegans

Alignment Length:	374	Identity:	70/374 - (18%)
Similarity:	120/374 - (32%)	Gaps:	115/374 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   563 LHSQASIEDAESNARLD---QTSSDSQISPSDEPAEKATTDILE-EEDLNG-------------- 609
            ||:. :.|.||...|.:   |...:.....:.:|..|...|::| :|:||.
Worm   324 LHAM-NDEHAEQARRAEGWLQMLKNDVAGVAKDPRFKKDEDLIERDEELNRMAAGGSGGPTSRQL 387

  Fly   610 ------QDREEDQEDYSVCDGPQSLPAILSGAHKLSDKFEQSGVFITDDEITVDIAKTEDQSVAN 668
                  :.||.::|::               ..|..:|||        :|...:.|:....:..:
Worm   388 AMREKIEQREREEEEW---------------RRKAKEKFE--------EEAAKNRARERKWAEEH 429

  Fly   669 TMGNPTPNLSK-----------IPRSPLAQRRRRSIDNSTCGGAGGSLQDLSSRSGLPAPAFSRK 722
            ....|....|:           ..::.|.|...:| :.||.........|:.:....|.|:.:..
Worm   430 GFNRPIRTRSQKYAEQDRIRYARKKAALEQSNEQS-NESTDDAVESDSDDVPAPQSPPTPSPADP 493

  Fly   723 QPVYRSVR-----TRNSTGATTTPVAPPRSRQATQLPMVRDVTNTWSGRTTGAPK--RRPPCTAD 780
            .|...|..     ..|:||.:..| ||    ||...|...|     .|.||.:..  :.|...|.
Worm   494 GPTTSSSSLTQDPASNATGFSDVP-AP----QAPPTPSPAD-----PGPTTSSSSLTQDPASNAT 548

  Fly   781 TFVAPTNGTGPAGSFE---------------------RNGKGRSSQILYDSN----GRRVRSGAP 820
            .|    :|:.|..|||                     ||.:....:.:..:|    |...|.|:.
Worm   549 GF----SGSSPPNSFEETRMMCEDASDGKKIDETRKYRNNRSSKCRAIIINNVVFCGMEKRIGSD 609

  Fly   821 GCTSSLT---------TSPVKNHASSPLAQQLLEAASSAKNDAQILEKM 860
            .....|:         ::...|..||.:.:.:.:...|...|:.|:..|
Worm   610 KDKKKLSKLFERLGYQSTSYDNLKSSEILETVRQFTQSNHGDSLIITIM 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pigs	NP_001245550.1	CH	22..159	CDD:237981
pigs	NP_001245550.1	GAS2	258..325	CDD:280367
csp-2	NP_001370851.1	pneumo_PspA	239..>533	CDD:411490	46/243 (19%)
		PHA03418	<475..>563	CDD:177646	26/101 (26%)
		CASc	581..824	CDD:237997	14/78 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900