Protein Alignment pigs and gas2l2

DIOPT Version :10

• Sequence 1: NP_572331.2
• Gene: pigs / 31596
• FlyBaseID: FBgn0029881
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: XP_002662207.2
• Gene: gas2l2 / 100331123
• ZFINID: ZDB-GENE-170206-1
• Length: 894
• Species: Danio rerio
• Alignment Length: 1042
• Identity: 276/1042 - (26%)
• Similarity: 433/1042 - (41%)
• Gaps: 304/1042 - (29%)

  Fly    10 RPFKSSEEYLEAMREDLAEWLSTLYPELSINADNFMDRLDTGVALCKHANYVRQAAVDYLARRQA 74
            :|||||||||.||:|||||||..|| .::|:.:..::.|:||..||.|||.|.:.|.|:|.|..|
Zfish    13 KPFKSSEEYLYAMKEDLAEWLGDLY-NINIDVNTILEMLETGALLCAHANNVTRVADDFLKRLGA 76

  Fly    75 RNKSMTRSMTSGLAGPILAMGNVHYLPAAKSGTFFARDNVSNFITWCRKSLKIIECLLFETDDLI 139
            ...            |:.|.| |.::.:|...||.|||||:|||.||||.:.|.:.|:||||||:
Zfish    77 TEI------------PLPASG-VTFVSSAHPATFLARDNVTNFINWCRKEMSIPDVLMFETDDLV 128

  Fly   140 MRKNEKHVILCLLEVARRGAKFGMLAPMLVQMERQIDREIAADIKANGAGCSENGTQTDALETGN 204
            :|||||:.:|||||||||.::|||.:|:|:|:|::|:.||..:::.:.
Zfish   129 LRKNEKNFVLCLLEVARRASRFGMASPVLIQLEQEIEEEIREEMEESA----------------- 176

  Fly   205 SSAATMTTITTTTVETDLYDDSDDSETEDDGDQNPVLMYGPQPQIITNDLKSLDEMVRDLVEKCT 269
                                                   .|:.|....::::|||||:.|:.:|:
Zfish   177 ---------------------------------------HPKSQRSLINIQNLDEMVQLLISRCS 202

  Fly   270 CPSQFPMVRVSEGKYRIGDTKVLIFVRILRSHVMVRVGGGWDTLSHYLDKHDPCRCRAQHRSSVA 334
            ||||||||:||:||||:||:..||||||||:|||||||||||||.|||||||||||     :|:.
Zfish   203 CPSQFPMVKVSDGKYRVGDSNTLIFVRILRNHVMVRVGGGWDTLEHYLDKHDPCRC-----TSLV 262

  Fly   335 ARLIPRQ-SPNH-------NP-SNGIELHKAQVIFERSPPAARRVFNSPN--CNGGPG-TGSSCG 387
            .:|..|. :|.|       :| .:|....:..::..|:....:.||.:|:  ..|.|. ..|||.
Zfish   263 HKLTARPVTPVHEIKERLTSPRPDGQCASQTTLMLSRTQSPLQSVFWTPSRAQKGWPSPPRSSCS 327

  Fly   388 TGVVGVAVP---PTLQNGHSLSPNSGKYRSRSPTPQRKFLNQQANGGGIASATGSSQTVTTDTSS 449
            ..      |   ||.:...|.|||  |.|.|..|||            :.:...|..::.|:::|
Zfish   328 PD------PEHQPTRRRNTSSSPN--KLRERPGTPQ------------MFTCPDSKDSLKTNSTS 372

  Fly   450 GQ---LLGSPSLAR------RSMSP---------SPRRLIDMRKKQSSLDSYSSGPKSLPGYSCS 496
            .:   ...:|.:.|      |::.|         .|:..:..::..:.:.:.....|:| |.:.:
Zfish   373 RKGRDATRTPPVPRLTSSLPRAIHPPTTPQPEIQRPQTPLVFQRNLNQVQTQQVPEKNL-GQTWT 436

  Fly   497 MEEANGGSGVGSAAGGVSSGSAGSGVAGEQGGANKFENISDNGSEISDEGYRSLGVIQSGAQKRE 561
            ..:........|.|||                         .|.|..|.    :...:|.::...
Zfish   437 KSQFVSKLRQHSTAGG-------------------------KGRENQDR----VDSQESPSRTFR 472

  Fly   562 SLHS-----QASIEDAESN------------------------ARLDQTSSDSQISPSDEPAEKA 597
            ::||     ..::|:||.|                        |:.::..:.::| |.:||:|||
Zfish   473 NIHSYPKPPNITVEEAEDNGGPKNSNFPRTFSPFKGLIGAILEAQFNRPRTQAKI-PQEEPSEKA 536

  Fly   598 TTDILEEEDLNGQDREEDQEDYSVCDGPQSLPAILSGAHKLSDKFEQSGVFITDDEITVDIAKT- 661
             .:||   ::|.:.:.|...|.::....|.|...|........|..||         .:|..|:
Zfish   537 -KNIL---NVNKRGQVEQAPDKAMSKKAQHLVLPLQSLLINPSKSYQS---------QLDPQKSK 588

  Fly   662 -----EDQSVANTMGNPTPNLS---------KIPRSPLAQRRRRSIDNSTCGGAGGSLQDLSSRS 712
                 ||.....:.....|.||         .:....||..::.|||:.|...:.....|.:.::
Zfish   589 AKFGGEDGGTERSYVFTPPPLSLAQEAVLYKSLEEEILANLQQLSIDSETSTSSDEKHHDETLKN 653

  Fly   713 GLPAPAFSRKQPVYRSVRTRNSTGATTTPVAPPRSRQATQLPMVRDVTNTWSGRTTGAPKRRPPC 777
                   |||.|......:..|  |:.....|.|..:|....:         ...:||.:.....
Zfish   654 -------SRKIPSDHCKASNRS--ASLDRATPKRGNRAFDAVI---------AELSGAQRNLEKV 700

  Fly   778 TADTFVAPTNGTGPAGSFERNGKGRSSQILYDSNGRRVRSGAPGCTSSLTTSPVKNHASSPLAQQ 842
            :.:.:|    .|.|.|   ..||...|.    :....::...|..|||.::
Zfish   701 SVEKWV----NTLPKG---LKGKTEDSH----TTTHHLKVSKPCMTSSWSS-------------- 740

  Fly   843 LLEAASSAKNDAQILEKMKSLLSRYAAGNQTKAGVGATATAANKINSNGKKTPVYEDFTTAWVHS 907
             |.::..:|..|:|:     ::....:..:||..:|..::..|:   :.||            ..
Zfish   741 -LGSSMDSKETAEIV-----MVQVENSNLETKIPIGRVSSLGNE---HVKK------------QR 784

  Fly   908 NGNLERSESCSPPAKARSKRSSAASSCESNNSNAGAGSGAAAGSASVVSPRR----ERGMSKIPA 968
            :.:.::..|...|.:..|........|                    |.|||    ::..||||.
Zfish   785 SSSFKQRRSLRKPERVPSIFKLKLRPC--------------------VRPRRDPRSDQKPSKIPK 829

  Fly   969 PV 970
            ||
Zfish   830 PV 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pigs	NP_572331.2	CH_GAS2L1_2	11..163	CDD:409117	77/151 (51%)
		GAS2	257..325	CDD:460480	53/67 (79%)
gas2l2	XP_002662207.2	CH_GAS2L1_2	14..152	CDD:409117	77/151 (51%)
		GAS2	190..258	CDD:460480	53/67 (79%)