Protein Alignment CG14443 and Ddx50

DIOPT Version :10

• Sequence 1: NP_572330.2
• Gene: CG14443 / 31595
• FlyBaseID: FBgn0029880
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: NP_444413.1
• Gene: Ddx50 / 94213
• MGIID: 2182303
• Length: 734
• Species: Mus musculus
• Alignment Length: 598
• Identity: 121/598 - (20%)
• Similarity: 232/598 - (38%)
• Gaps: 146/598 - (24%)

  Fly   189 KTSRENKESRSRSSSLPQKRFCPSKTQNDLT--YGSPEPKSPSNRGR--NSWRVGMR-----TPW 244
            :.||.:.||..|:.:          .:|.:|  ..:|:||....|.:  ...:.|:|     :|.
Mouse    33 RKSRHHSESEERTET----------RENGVTDDLDAPKPKKAKMREKLNGDTKEGLRFSDEFSPS 87

  Fly   245 KKSQSRSMSCSSIQKILVSRSFTRSRSPHRNTLCYQDQSKNPSRPSNYNTWKQPMDEVYNNAANY 309
            .||:.:.:....:.:                   |:.:||..|...|.:......:|
Mouse    88 HKSRRKDLPNGDVDE-------------------YEKRSKRVSSSENSHKSSDKAEE-------- 125

  Fly   310 RKRHNITLTSWNMRNLPEPVLSFERSGFNATILQQLEDQGYDGPTPIQAQTWSIAKEGKNIVMIS 374
                  |||    |...|.  :|.....:...::.|:.:|.....|||.:|:....|||:::..:
Mouse   126 ------TLT----REQKEG--AFSNFSISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQA 178

  Fly   375 GKGTGKTLGYLLPGIMKMHNQRGLMQHKKGPIVLILVDCREAAVMVQREVLYYTNPLELRTHCLL 439
            ..|||||..:.:|.|.::...:..::..:.|.||:|...||.|..|.::....|..|.:.  |..
Mouse   179 RTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSVA--CFY 241

  Fly   440 GNSQWQGHAE-----CDLLVASAGRLLQMIDNKKHV----VELERCTYLVLDNIDRMIDVGLEGN 495
            |.:.:|....     .|:||.:.||:      |.|:    ::|.:..::|||.:|:|:|:|....
Mouse   242 GGTSYQSQINQIRNGIDILVGTPGRI------KDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQ 300

  Fly   496 ICRLLCRLRPHAQLIVSSTS------WSSNLKRMANKFLGQYTAIRVGEINNIGVRLQNIRQRVE 554
            :..::     |......|..      :|:...:...|...:|...|..:::.:|...|.....||
Mouse   301 VEDII-----HESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVE 360

  Fly   555 ---VVNGLSKVERLMKELTAIYDTSDIPGKVVIYVKRQKVVEELV--DLIRNCVPCEGIHGGRTA 614
               :....|:...::.::..:|..|:  |:.:|:.:.:|.|.|:.  ..|:....|  :||....
Mouse   361 HLAIQCHWSQRPAVIGDVLQVYSGSE--GRAIIFCETKKNVTEMAMNPHIKQNAQC--LHGDIAQ 421

  Fly   615 QENQGIIHDFGTGAYNIIVATQMTSNCLDVPGIRYVINYDFPDNIDKYVQRMSRTG-------CL 672
            .:.:..:..|..|::.::|||.:.:..||:|.:..||....|.:::.|:.|..|||       |:
Mouse   422 SQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICV 486

  Fly   673 SY---------------------------------NRNCEVISFFTMANYKLVTEVVDFLKICKQ 704
            .:                                 :::.:.|......:|    ..|||.:
Mouse   487 CFYQPRERGQLRYVEQKAGITFKRVGVPSTMDLVKSKSMDAIRSLASVSY----AAVDFFR---- 543

  Fly   705 EIGPHLLQLAEEK 717
               |...:|.|||
Mouse   544 ---PSAQRLIEEK 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14443	NP_572330.2	DEAD-like_helicase_N	<310..720	CDD:475120	99/468 (21%)
Ddx50	NP_444413.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..131		26/144 (18%)
		Q motif	134..162		5/29 (17%)
		SrmB	136..523	CDD:440279	84/403 (21%)
		DEVD box	287..290		1/2 (50%)
		GUCT_RHII_Gualpha_beta	565..656	CDD:240593
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	664..734