DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14443 and STRS1

DIOPT Version :9

Sequence 1:	NP_572330.2	Gene:	CG14443 / 31595	FlyBaseID:	FBgn0029880	Length:	736	Species:	Drosophila melanogaster
Sequence 2:	NP_174479.1	Gene:	STRS1 / 840087	AraportID:	AT1G31970	Length:	537	Species:	Arabidopsis thaliana

Alignment Length:	575	Identity:	140/575 - (24%)
Similarity:	247/575 - (42%)	Gaps:	114/575 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 QSPNSFKAVKTSRENK--ESRSRSSSLPQKRFCPSKTQNDLTYGSPEPKSPSNRGRNSWRVGMRT 242
            :||.:.|..|.|::||  |.......:||          ::|.|..|..|...:
plant    18 ESPMTNKKKKKSKKNKHTEENHEVEEVPQ----------EVTNGVEEELSNKEK----------- 61

  Fly   243 PWKKSQSRSMSCSSIQKILVSRSFTRSRSPHRNTLCYQDQSKNPSRPSNYNTWKQPMDEVYNNAA 307
              ||.:.|....|...|        :...|.:. |..:|..:..|.........:.::|     |
plant    62 --KKKRKREEKESEKNK--------KKDVPEKK-LEAEDLGEGESEQQKVVVTGKGVEE-----A 110

  Fly   308 NYRKRHNITLTSWNMRNLPEPVL----SFERSGFNATILQQLEDQGYDGPTPIQAQTWSIAKEGK 368
            .|     ..|.::...||||.||    :||:                  |:|||:.||....:|:
plant   111 KY-----AALKTFAESNLPENVLDCCKTFEK------------------PSPIQSHTWPFLLDGR 152

  Fly   369 NIVMISGKGTGKTLGYLLPGIM---KMHNQRGLMQHKKGPIVLILVDCREAAVMVQREVLYYTNP 430
            :::.|:..|:||||.:.:|.||   |.:.:.|....|..|..|:|...||.||.:...:.....|
plant   153 DLIGIAKTGSGKTLAFGIPAIMHVLKKNKKIGGGSKKVNPTCLVLSPTRELAVQISDVLREAGEP 217

  Fly   431 LELRTHCLLGNSQWQG------HAECDLLVASAGRLLQMIDNKKHVVELERCTYLVLDNIDRMID 489
            ..|::.|:.|.|. :|      .:..|:::.:.|||..:|::  :|:.|...:::|||..|||:|
plant   218 CGLKSICVYGGSS-KGPQISAIRSGVDIVIGTPGRLRDLIES--NVLRLSDVSFVVLDEADRMLD 279

  Fly   490 VGLEGNICRLLCRLRPHAQLIVSSTSWSSNLKRMANKFLGQYTAIRVGEINNIGVRL-------- 546
            :|.|..:..:|.......|:::.|.:|..::.::|.:|:         :.|.|.|.:
plant   280 MGFEEPVRFILSNTNKVRQMVMFSATWPLDVHKLAQEFM---------DPNPIKVIIGSVDLAAN 335

  Fly   547 QNIRQRVEVVNGLSKVERLMKELTAIYDTSDIPGKVVIYVKRQKVVEELVDLIRNCVPCEG---- 607
            .::.|.:||::..::.:||:..|...:.:.  ..:|:::...:...|.|...::.    .|
plant   336 HDVMQIIEVLDERARDQRLIALLEKYHKSQ--KNRVLVFALYKVEAERLERFLQQ----RGWKAV 394

  Fly   608 -IHGGRTAQENQGIIHDFGTGAYNIIVATQMTSNCLDVPGIRYVINYDFPDNIDKYVQRMSRTGC 671
             |||.:...|....:..|..|:..::|||.:.:..||:|.:..||||.||...:.||.|:.|||
plant   395 SIHGNKAQSERTRSLSLFKEGSCPLLVATDVAARGLDIPDVEVVINYTFPLTTEDYVHRIGRTG- 458

  Fly   672 LSYNRNCEVISFFTMANYKLVTEVVDFLKICKQEIGPHLLQLA------EEKMFG 720
             ...:.....:|||..|..|..|:|:.|:...|.:...||:..      |.|::|
plant   459 -RAGKKGVAHTFFTPLNKGLAGELVNVLREAGQVVPADLLKFGTHVKKKESKLYG 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14443	NP_572330.2	P-loop_NTPase	332..535	CDD:304359	56/211 (27%)
		DEXDc	345..544	CDD:214692	56/207 (27%)
		Helicase_C	560..670	CDD:278689	29/114 (25%)
STRS1	NP_174479.1	PTZ00110	83..513	CDD:240273	120/479 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0331
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900