Protein Alignment CG14443 and Ddx43

DIOPT Version :9

• Sequence 1: NP_572330.2
• Gene: CG14443 / 31595
• FlyBaseID: FBgn0029880
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: XP_003750593.1
• Gene: Ddx43 / 682138
• RGDID: 1586947
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 694
• Identity: 171/694 - (24%)
• Similarity: 309/694 - (44%)
• Gaps: 136/694 - (19%)

  Fly   123 RSSSESAHSSGSESSSSDSNSGSSSDSDSTTGS-----SSHGSDTGERPRMRSAVFRIHETWQSP 182
            |.|:.:|.|||..|..|.:.|..:..:.:..|:     .|.|:..|               |:.|
  Rat     4 RESAANASSSGVASRRSSTGSRGAERTATEEGNRRGRVGSRGAGGG---------------WREP 53

  Fly   183 NSFKAVKTSRENKESR--------------SRSSSLPQKRFCPSKTQNDLTYGSPEPKSPSNRGR 233
             :..|..|:...:|..              .|..|..::....:.|:..:..|:||.:.
  Rat    54 -AGAAEATAASRREPPLCFGVKNDVVGAVIGRGGSKIREIQNTTNTRIQVIKGNPEAEI------ 111

  Fly   234 NSWRVGMRTPWKKSQSRSMSCSSIQKILVSRSFTRSRS---PHR-NTLCYQDQSKNPSRPSNYNT 294
                       |...:::|...:  |.::.....:.::   .|| :.:.:|......:..|...|
  Rat   112 -----------KIFGNKAMQTKA--KTVIDNVVKKQQNYIPGHRVDIIAFQPTVGTDTSTSESVT 163

  Fly   295 WKQPM---DEVYNNAANYRKR----------------------HNITLTSWNMRN---------- 324
            ..||:   |::..:|..:.|:                      ..:.:.:|...|
  Rat   164 DDQPLIDWDQIREDALKWEKKKWADLPPIKKNFYIESATTSSMSQVQIDNWRKENFNITCDDLKD 228

  Fly   325 -----LPEPVLSFERSGFNA--TILQQLEDQGYDGPTPIQAQTWSIAKEGKNIVMISGKGTGKTL 382
                 :|.|:..|| ..|::  .:::.::..|:..|||||:|.|.|..:|.:::.::..||||||
  Rat   229 GEKRPIPNPICKFE-DAFHSYPEVMENIKRAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTL 292

  Fly   383 GYLLPGIMKMHNQRGLMQHKKGPIVLILVDCREAAVMVQREVLYYTNPLELRTHCLLGNSQWQGH 447
            .||:||.:.:.:|....:.:.||.:|:|...||.|:.|:.|...|:.. :|::.|:.|.....|.
  Rat   293 SYLMPGFIHLDSQPLAREQRNGPGMLVLTPTRELALQVEAECSKYSYG-DLKSVCVYGGGDRDGQ 356

  Fly   448 AE-----CDLLVASAGRL--LQMIDNKKHVVELERCTYLVLDNIDRMIDVGLEGNICRLLCRLRP 505
            .:     .|:::|:.|||  |||    .:.|.|:..||||||..|:|:|:|.|..|.::|..:||
  Rat   357 IQDVSKGVDIIIATPGRLNDLQM----NNFVNLKSVTYLVLDEADKMLDMGFEPQIMKILLDVRP 417

  Fly   506 HAQLIVSSTSWSSNLKRMANKFLGQYTAIRVGEINNIGVRLQNIRQRVEVVNGLSKVERLMKELT 570
            ..|.|::|.:|...::|:|..:|.:...:.||.::.:.|  ..::|.:.:    :..|.....:.
  Rat   418 DRQTIMTSATWPYAVRRLAQSYLKEPMIVYVGTLDLVAV--STVKQNIII----TTEEEKRTHIQ 476

  Fly   571 AIYDTSDIPGKVVIYVKRQKVVEEL-VDLIRNCVPCEGIHGGRTAQENQGIIHDFGTGAYNIIVA 634
            ...:......||:::|.|:.|.:.| .|||...:..|.:||.|...:.:..:.:|.||...|::|
  Rat   477 TFLENMSPKDKVIVFVSRKAVADHLSSDLILRHISVESLHGNREQSDREKALENFKTGKVRILIA 541

  Fly   635 TQMTSNCLDVPGIRYVINYDFPDNIDKYVQRMSRTGCLSYNRNCEVISFFTMANYKLVTEVVDFL 699
            |.:.|..|||..|.:|.|||||.||::||.|:.|||  ...|....|:..|..::::.||:::.|
  Rat   542 TDLASRGLDVHDITHVYNYDFPRNIEEYVHRVGRTG--RAGRTGMSITLITRNDWRIATELINIL 604

  Fly   700 KICKQEIGPHLLQLAE-----------EKMFGPRQRRRHRPQRY 732
            :...|.|...|:.:||           ||..|   |.:.:||::
  Rat   605 ERANQNIPEELVLMAERYKANKLKREMEKKMG---RPQGKPQKF 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14443	NP_572330.2	P-loop_NTPase	332..535	CDD:304359	70/211 (33%)
		DEXDc	345..544	CDD:214692	69/205 (34%)
		Helicase_C	560..670	CDD:278689	37/110 (34%)
Ddx43	XP_003750593.1	KH-I	68..133	CDD:412160	9/83 (11%)
		PTZ00110	153..642	CDD:240273	139/505 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910