Protein Alignment CG14443 and ddx59

DIOPT Version :10

• Sequence 1: NP_572330.2
• Gene: CG14443 / 31595
• FlyBaseID: FBgn0029880
• Length: 736
• Species: Drosophila melanogaster
• Sequence 2: NP_001038443.2
• Gene: ddx59 / 562123
• ZFINID: ZDB-GENE-050208-665
• Length: 584
• Species: Danio rerio
• Alignment Length: 654
• Identity: 137/654 - (20%)
• Similarity: 260/654 - (39%)
• Gaps: 133/654 - (20%)

  Fly   122 LRSSSE--SAHSSGSESSSSDSNSGSSSDSDSTTGSSSHGSDTGERPRMRSAV--FRIHETWQSP 182
            |:.:||  ..|...|:.:|.:..:.:::.:.:|...|....:..|:..:...|  |:..:.|..|
Zfish     9 LKRASEPPQQHPKRSKPTSEEDTAVTAAPAVNTEEESRQTDNEEEQQEIEEPVKSFKKSQRWPEP 73

  Fly   183 NSFKAVKTSRENKESRSRSSSLPQKRFCPSKTQNDLTYGSPEPKSPSNRGRNSWRVGMRTPWKKS 247
            .....|...|..:             :...||.||:.
Zfish    74 GEPVCVMCGRYGE-------------YICDKTDNDIC---------------------------- 97

  Fly   248 QSRSMSCSSIQKILVSRSFTRSRSPHRNTLC--YQDQSKNPSRPSNYNTWKQPMDEVYNNAANYR 310
               |:.|               ::.|...:|  :.|:..|     |.||     .|...|..||.
Zfish    98 ---SLEC---------------KAAHLAAVCADFGDKLFN-----NKNT-----PESSENTKNYC 134

  Fly   311 KRHNITLTSWNMRNLP----------------EPVLSFERSGFNATILQQLEDQGYDGPTPIQAQ 359
            .:.:..::......:.                .||:.|:...|...:.:.|:..||:.|||:|.|
Zfish   135 YKEDTFISELTEEQIERVKAELGIVSVGTEVCRPVIEFQHCRFPTVLEKNLKVAGYEAPTPVQMQ 199

  Fly   360 TWSIAKEGKNIVMISGKGTGKTLGYLLPGIMKMHNQRGLMQHKKG---PIVLILVDCREAAVMVQ 421
            ...:...|::::..:..|:|||:.:|||.:|     |.|......   |..|||...||.|:.::
Zfish   200 MVPVGLTGRDVIATADTGSGKTVAFLLPVVM-----RALQSESASPSCPACLILTPTRELAIQIE 259

  Fly   422 REVLYYTNPL-ELRTHCLLGNSQW--QGHA---ECDLLVASAGRLLQMIDNKKHVVELERCTYLV 480
            .:.......| .:||..|:|....  |.|.   ...:::.:.||||:::  |:..::|:....:|
Zfish   260 EQAKELMRGLPNMRTALLVGGMPLPPQLHRLKHNIKIVIGTPGRLLEIL--KQKAIQLDHVRTVV 322

  Fly   481 LDNIDRMIDVGLEGNICRLLCRLRPHAQLIVSSTSWSSNLKRMANKFLGQYTAIRVGEINNIGVR 545
            :|..|.|:.:|.:..:..:|.::....|.:::|.:..:..:::|.:.......|.:|:.|.   .
Zfish   323 VDEADTMLKMGFQQQVLDILEQVPEDHQTLLTSATIPTGTQQLAERLTHDPVTITIGQKNQ---P 384

  Fly   546 LQNIRQRVEVVNGLSKVERLMKELTAIYDTSDIPGKVVIYVKRQKVVEELVDLIRNCVPCE--GI 608
            ..|:||.|..|...||.::|.:.|.   |.......||::|..:...:.|.:.::..:...  .|
Zfish   385 CANVRQIVLWVEEPSKKKKLFEILN---DEKLYQPPVVVFVDCKLGADLLCEAVQKVMSLNTVAI 446

  Fly   609 HGGRTAQENQGIIHDFGTGAYNIIVATQMTSNCLDVPGIRYVINYDFPDNIDKYVQRMSRTGCLS 673
            |..:...|...|:.....|.::::::|.:....||:..::.|||:|.|.|:|:||.::.|.|.|.
Zfish   447 HSDKMQWERNKIVKGLLEGQFDVVISTGILGRGLDLVNVKLVINFDMPSNMDEYVHQIGRAGRLG 511

  Fly   674 YNRNCEVISFFTMANYKLVTEVVDFLK----ICKQEI--GPHLLQLAEEKMFGPRQRRRHRPQRY 732
            :...  .|:|....|.:|..|:|..:|    |...:|  .|||.:          |:||.:.:..
Zfish   512 HRGT--AITFMNNNNKRLFLEMVKRVKPTGSILPPQILNSPHLHE----------QQRRDKQKNT 564

  Fly   733 NRMH 736
            ...|
Zfish   565 QHTH 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14443	NP_572330.2	DEAD-like_helicase_N	<310..720	CDD:475120	101/442 (23%)
ddx59	NP_001038443.2	PLN00206	60..562	CDD:215103	127/595 (21%)